New option to treat addictionLauran Neergaard
“This doesn’t seem like it’s working the way we had hoped,” said Suen, an assistant professor at the UCSF Division of General Internal Medicine and an addiction medicine specialist. “But when people expect it to work, and it doesn’t work for them, they feel like there’s something...
Stimulating the vagus nerve of rats deters them from seeking cocaine, suggesting that this therapy could help treat drug addiction and prevent relapse in substance use disorders. The vagus nerve is a bundle of nerve fibres connecting the brain to most internal organs. Previous research has shown ...
In spite of its structural relationship to amphetamine, methylphenidate resembles in many ways a more benign version of cocaine, yet with a much longer half-life. Methylphenidate blocks the reuptake of, but doesn't significantly release, the catecholamines noradrenaline and dopamine. If it is taken...
and although they are very similar to each other, the differences between the proteins may help explain why some compounds can cause side effects such as hallucinations,” Han said. “By learning how each of the proteins binds to the kappa receptor, we expect to find ways to activate that ...
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National centre for advancing translational sciences (NCATS), an initiative from of national institute of health (NIH) in the united states of america (USA), defined drug repurposing as “studying the drugs that are already approved to treat one disease or condition to see if they are safe ...
This work suggests it is possible to design a drug that only targets the pain pathway, without side effects. These kind of drugs are called “biased” opioids. Discovering and designing drugs to target KOR So far, there are two popular ways to discover new drugs. The first involves...
But what is novel is the potential ways GLP-1RA drugs can negatively affect the pancreas and kidneys. While these adverse effects are uncommon, they can be very serious; physicians must be vigilant for signs of pancreatitis and monitor kidney function among people taking GLP-1RA medications...
The drug has become the most commonly available psychedelic therapy. Read more Why the mind-body connection is vital to understanding consciousness That might sound like good news given the mounting evidence that ketamine can treat depression, post-traumatic stress disorder and addict...