The deaths last month of two patients in a clinical trial testing a promising new type of cancer treatment are raising questions about the fate of therapies that use a patient’s own immune cells to fight off the disease. Juno Therapeutics, the Seatt
The invention here relates to a product comprised of a cell line or lines intended for use as an allogeneic immunotherapy agent for the treatment of cancer in mammals and humans. All of the studies of cell-based cancer vaccines to date have one feature in common, namely the intention to ...
patent US8,399,645 has great commercial value. Another highly-discussed topic concerning novel cancer treatments is immune checkpoint inhibitor therapies, in which the primary proteins to be targeted areCTLA4 (cytotoxic T-lymphocyte-associated protein 4), PD-1 (programmed cell death protein 1) andP...
Ovarian cancer forms in the tissues of the ovaries, the female reproductive glands. Ovaries are made up of 3 main kinds of cells: cells that cover the outer surface of the ovary, germ cells that prod
Colorectal cancer or colon cancer is cancer of the large intestine (colon), which is the final part of the digestive tract. Both colon cancer and rectal cancer can be referred to as colorectal or bow
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The newest targeted therapies are helping doctors to tailor increasingly effective treatments to individual patients
molecules from genetically engineered mice, known as chimeric antigen receptors, or CARS. The cells are then infused back into the body. The CARS molecules reduce the ability of the cancer to shield itself from the patient's natural immune system, allowing the T-cells to attack the cancer. ...
Immunotherapy for cancer has made great advances and many patients can now receive effective treatments that were not available 10 years ago. However, there are certain types of cancer that do not respond to existing immunotherapy. A study from Karolinsk
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