New insights and treatments of kidney diseaseFocuses on kidney diseases in dogs. Different roles a kidney performs; Functioning units of the kidney; Reported kidney disease in young dogs due to gross malformation; S...
Presenters at the American Diabetes Association 84th Scientific Sessions analyzed potential developments in treatment for patients with diabetes and diabetic kidney disease. Diabetic kidney disease (DKD) is the leading cause of mortality for patients with type 2 diabetes (T2D), with almost half of ...
Kidney Cancer: New Treatments Bring New Hope TV Episode Edit pageAdd to list Until a few years ago, patients with kidney cancer did not have many treatment choices. Surgery and/or difficult-to-tolerate immunotherapy were all that was available. Today, new options for robotically assisted surgery...
In 2019, FDA approved new indications for canagliflozin to reduce the risk of ESRD, kidney function deterioration, cardiovascular death and hospitalization for heart failure in patients with T2DM and CKD. Subsequently, based on the findings of the CREDENCE trial, the American Diabetes Association (ADA...
Potential new treatments for diabetic kidney disease. Kania Deanna S,Smith Cory T,Nash Christy L,Gonzalvo Jasmine D,Bittner Andrea,Shepler Brian M. The Medical Clinics of North America . 2013Deanna S. Kania, Cory T. Smith, Christy L. Nash, Jasmine D. Gonzalvo, Andrea Bittner, Brian M. ...
Metastatic colorectal cancer (CRC) is still in need of effective treatments. This study applies a holistic approach to propose new targets for treatment of primary and liver metastatic CRC and investigates their therapeutic potential in-vitro. An integrative analysis of primary and metastatic CRC sampl...
The inhibitors were then tested in mice that had been genetically altered to produce a condition similar to PKD. Animals treated with CFTR inhibitors for up to seven days had significantly slower cyst expansion and kidney enlargement, and better preservation of kidney function. There was no evidence...
This understanding of the genetic pathways that regulate auditory function has revealed new targets for pharmacological treatment of the disease. Moreover, approaches that are based on stem cells and gene therapy, which may have the potential to restore or maintain auditory function, are beginning to...
Research could also lead to cell therapies for cardiac disease. In particular, human pluripotent stem cells could be used to create regenerative heart medications that reverse tissue damage and trigger protective responses. Like the other cell-based treatments, it’s an extremely challenging, but pote...
A team led by Vineet Gupta, PhD and Jochen Reiser, MD, PhD (Rush University Medical Center) has now developed a system that can be used to identify noveldrug candidatesthat protect the function of kidney podocytes, cells that are critical for filtering the blood. Damage to these cells is ...