Neuropathy may be the most common complication of diabetes and can make walking difficult as well as leading to even more serious problems like losing a limb. Diabetic neuropathy is damage caused to the nerves, and it can result in numbness, tingling, burning, and pain. Until now the painkill...
diabetic neuropathy (DN) models that the multiple pathways involved in neuronal degeneration cause overproduction of reactive oxygen species, oxidative stress, and cellular dysfunction, therapeutic approaches addressing these mechanisms have not yet provided a basis for a successful treatment of patients ...
Efgartigimod is also being studied for treatment of other autoimmune diseases such as chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), myositis, pemphigus vulgaris, and primary immune thrombocytopenia (ITP). A real-world evidence study comparing efgartigimod to conventional therapy ...
Treatment-induced neuropathy of diabetes: an acute, iatrogenic complication of diabetes. Brain 138, 43–52 (2015). Article PubMed Google Scholar Cazzato, D. et al. Small fiber neuropathy is a common feature of Ehlers-Danlos syndromes. Neurology 87, 155–159 (2016). Article PubMed PubMed...
First, what causes neuropathy? One cause can be that the cancer tumor is growing or pressing on a nerve. Other causes can come directly from cancer treatments. For example, radiation can be a cause of nerve damage, and sometimes you might not notice symptoms for years after treatment. Surger...
Antiviral Medications for Treatment of Nonsevere InfluenzaA Systematic Review and Network Meta-Analysis Ya Gao, PhD; Yunli Zhao, MD; Ming Liu, PhD; et al. Abstract Full Text JAMA Intern Med. Published online January 13, 2025. doi:10.1001/jamainternmed.2024.7193 This systematic review and...
The goal of induction therapy is to discontinue steroids 3–6 months after starting treatment; many Japanese clinicians recommend the low-dose maintenance therapy for up to 3 years [113]. In type1 AIP (IgG4-related pancreatitis), a Japanese RCT study for usefulness of low-dose maintenance Tx...
It isn’t exactly an impressive feat for a 57-year-old woman—except that Gómez is blind. And she’s been that way for over a decade. When she was 42, toxic optic neuropathy destroyed the bundles of nerves that connect Gómez’s eyes to her brain, rendering her totally without s...
treatmentfailures[1316].Althoughtheresponserateto inductionchemotherapyisapproximay3040%,long- B.LuL.SunX.YanZ.AiJ.Xu()termsurvivalremainsunchanged[13]. DepartmentofThoracicSurgery,TheAffiliatedHospital Athree-drugtinum-basedregimen,withtheaddition ...
14“There was obviously more alopecia, neuropathy, and neutropenia with paclitaxel/trastuzumab; and there were more liver function test [result] abnormalities, thrombocytopenia, and early discontinuation before 1 year with T-DM1,” Krop said. Despite the higher incidence of neurotoxicity in the ...