Neuropathy may be the most common complication of diabetes and can make walking difficult as well as leading to even more serious problems like losing a limb. Diabetic neuropathy is damage caused to the nerves, and it can result in numbness, tingling, burning, and pain. Until now the painkill...
diabetic neuropathy (DN) models that the multiple pathways involved in neuronal degeneration cause overproduction of reactive oxygen species, oxidative stress, and cellular dysfunction, therapeutic approaches addressing these mechanisms have not yet provided a basis for a successful treatment of patients ...
Efgartigimod is also being studied for treatment of other autoimmune diseases such as chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), myositis, pemphigus vulgaris, and primary immune thrombocytopenia (ITP). A real-world evidence study comparing efgartigimod to conventional therapy ...
Treatment-induced neuropathy of diabetes: an acute, iatrogenic complication of diabetes. Brain 138, 43–52 (2015). Article PubMed Google Scholar Cazzato, D. et al. Small fiber neuropathy is a common feature of Ehlers-Danlos syndromes. Neurology 87, 155–159 (2016). Article PubMed PubMed...
Treatment options for hearing loss are mostly based on medical devices, including hearing aids and cochlear implants; there are no pharmacological therapeutics currently in widespread use. Hair cells in the inner ear are the sensory cells for the detection of sound; hair cells are frequently affected...
Reference: “Safety and efficacy of leriglitazone for preventing disease progression in men with adrenomyeloneuropathy (ADVANCE): a randomised, double-blind, multi-centre, placebo-controlled phase 2–3 trial” by Wolfgang Köhler, Marc Engelen, Florian Eichler, Robin Lachmann, Ali Fatemi, Jacinda...
Lung cancer leads in causing cancer-related mortality worldwide, continually posing a significant threat to human health. Current imaging diagnostic techniques, while offering non-invasive detection, suffer from issues such as insufficient sensitivity an
In a news release, the company indicated the data further advance the depth of clinical and real-world evidence supporting the use of faricimab (Vabysmo), the first and only bispecific antibody for the eye, for the treatment of neovascular or ‘...
New perspective on diabetic neuropathy pathogenesis and treatmentInpharma Weekly -doi:10.2165/00128413-199409320-00003NoneSpringer International PublishingInpharma Weekly
2023b; Rais et al.2023). Elranatamab has been approved for relapsed or refractory multiple myeloma after four or more prior therapies following priority review, breakthrough, and orphan drug designation (Dhillon2023b). Elranatamab is well tolerated, and the most common non-hematologic treatment-...