Atopic dermatitis (AD) is a common chronic pruritic inflammatory cutaneous disease. AD is characterized by intense pruritus and enormous clinical heterogeneity. Treatment goals are to improve skin lesions and minimize exacerbations and symptom burden. Currently, topical corticosteroids (TCS) and topical ca...
New topical treatments for atopic dermatitis: Active comparators are neededAtopic dermatitisatopic eczemaclinical trialscomparative effectiveness researcheczemadoi:10.1016/j.jaad.2021.06.002Hywel C. WilliamsJournal of the American Academy of Dermatology
Paul, C. (2012), New topical drug development in atopic dermatitis: a place for hope. British Journal of Dermatology, 166: 711. doi: 10.1111/j.1365-2133.2012.10913.x Author Information Paul Sabatier University and Department of Dermatology, Hôpital Larrey, 24 chemin de Pouvourville, 31000...
New treatments for atopic dermatitis.New treatments for atopic dermatitis.Editorial. Comments on the use of tacrolimus and pimecrolimus to treat atopic dermatitis in children. Lack of clinical trials to test and compare treatments; Comparison of tacrolimus and pimecrolimus to topical corticosteroids; Safet...
APPROVAL has been granted by the FDA for lebrikizumab-lbkz in treating moderate to severe atopic dermatitis (AD) in patients aged 12 and older. This IL-13 inhibitor is designed for individuals who haven’t responded adequately to topical therapies, including pediatric patients weighing at least 88...
topical therapyAtopic eczema (AE) is a chronic relapsing inflammatory skin condition and one of the most common, potentially debilitating diseases with increasing incidence.The complex etiology of AE with multiple systemic and local immunologic and inflammatory responses and interactions between ...
FDA Approval for Nemluvio (nemolizumab) for Patients with Moderate-to-Severe Atopic Dermatitis Nemluvio approval historyVtama (tapinarof) Cream New Indication Approved: December 12, 2024 Date of Original Approval: May 23, 2022 Vtama (tapinarof) is a topical aryl hydrocarbon receptor (AhR...
Steroid drugs, either topical or systemic, have been one of the few ways to treat atopic dermatitis, but they have a wide range of side effects that make long-term treatment a concern. Moisturizing creams, lotions, special diets and other approaches have shown limited success. ...
Ramla Salad, Pharma Analyst at GlobalData, comments:“Cara has launched a Phase III trial, KIND-1 (NCT05387707), to evaluate the efficacy and safety of oral difelikefalin as an adjunctive therapy to topical corticosteroids (TCS) for moderate to severe pruritus in adult subjec...
Topical Application with a New NF-|[kappa]|B Inhibitor Improves Atopic Dermatitis in NC|[sol]|NgaTnd Mice Tanaka A, Muto S, Jung K, Itai A, Matsuda H. Topical application with a new NF-κB inhibitor improves atopic dermatitis in NC/NgaTnd mice. J. ... A Tanaka,S Muto,K Jung,.....