New antiepileptic drugs as add-on treatments DRUG REFRACTORY LOCALISATION RELATED EPILEPSY New antiepileptic drugs are licensed as add-on treatments in the first instance, efficacy and safety having been demonstrated in randomised placebo controlled add-on trials, with additional safety data predominantly ...
S. New GABA-targeting therapies for the treatment of seizures and epilepsy: I. role of GABA as a modulator of seizure activity and recently approved medications acting on the GABA system. CNS Drugs 37, 755–779 (2023). Article CAS PubMed PubMed Central Google Scholar Perucca, E., White...
A related question Thippeswamy is investigating is why a small fraction that develops the disorder doesn't respond to the most commondrugtreatments for epilepsy. Thippeswamy said medical science has a poor understanding of why only some people who have a seizure develop epilepsy – sometimes years...
Your child has a higher risk for another seizure within the next 2 years.What causes a seizure?The cause of your child's seizure may not be known. A seizure may be caused by any of the following:Epilepsy A head injury or a brain tumor Certain medicines, such as general anesthetics A ...
"It has long been thought the diet was effective due to its production of ketones, however we now believe the increase in levels of the fatty acid, decanoic acid, also produced by the diet, may provide the powerful antiseizure effects. ...
Meaning Despite availability of many new antiepileptic drugs with differing mechanisms of action, outcomes in newly diagnosed epilepsy have not improved; developing new disease-modifying compounds to current add to seizure-suppressing drug treatments may be necessary. Abstract Importance A study published ...
Opinions towards treatment are further complicated because an antiepileptic drug might be of some benefit for the control of one type of seizure while aggravating another type. Concomitantly, polytherapy increases the potential for adverse events. The ultimate goal of epilepsy treatment is to achieve ...
For more than 30 years, we have provided solutions that have helped transform the epilepsy landscape and improved the lives of millions of people. Our scientists have developed several life-changing solutions, providing individualized treatments to help people living with epilepsy.Utilizing...
Summary Objective We aim to develop a new scale that predicts seizure outcomes after resective epilepsy surgery. Methods We retrospectively reviewed patients who underwent surgery for medically refractory epilepsy at our center between 1999 and 2012. Four predictive outcome indicators were selected: preoper...
therapeutic components of phytocannabinoids - cannabinoids extracted from the C. sativa plant that limit or abolish such seizures. We hope that these findings will lead to new, better tolerated and more effective treatments for people with epilepsy, reducing the number and severity of seizure episodes...