Osteoarthritis (OA) is the most common form of arthritis and is among the top 10 conditions contributing to Years Lived with Disability—a measure reflecting the impact an illness has on quality of life before it resolves or leads to death. To date, no treatments are approved that slow diseas...
New treatments for osteoarthritis must be based on evidencedoi:10.1016/S2665-9913(19)30133-XFiona E WattThe Lancet Rheumatology
A new review by David A. Walsh and Joanne Stocks in theSeptember 2017 issue ofSLAS Discovery(formerly theJournal of Biomolecular Screening) explores evolving treatments and future therapies for osteoarthritis (OA) pain. It covers the limitations of existing treatments and introduces the latest understa...
Intraarticular Treatments for Osteoarthritis: New Perspectives To date, no targeted treatments for osteoarthritis have been developed. Therefore the challenge for the next years is to find a treatment that may slow dow... X Chevalier - 《Current Drug Targets》 被引量: 68发表: 2010年 Genicular ...
Research and Testing, Berlin, have discovered that the characteristic toughness and stiffness of bone is predominantly due to the presence of specialized sugars, not proteins, as had been previous believed. Their findings could have sweeping impacts on treatments for osteoporosis and other bone ...
Basic research on osteoarthritis has been carried out mainly from the his tological and biochemical aspects of the degenerating chondrocytes, collagen fibers, and matrix proteoglycans. Undue mechanical stress has been shown to be the pri... S Tanaka,C Hamanishi - Springer Japan 被引量: 3发表: ...
It has been shown that GF mice and antibiotic-treated mice serve as effective experimental models for demonstrating the regulation of bone metabolism by the GM. However, they are not considered suitable as screening models for identifying probiotics as potential treatments for OP. The use of GF an...
Osteoarthritis (OA) is a progressive disorder with high incidence in the ageing human population that still has no treatment currently. This disorder induces the breakdown of articular cartilage, leading to the exposure and damage of bone surfaces. For a global understanding of OA development, the ...
osteoarthritis. Intriguingly, it does this by a different mechanism than any other known anti-inflammatory painkiller, through affecting the last step of making a messenger RNA, polyadenylation. This means that medicines derived from cordycepin may help patients for whom other treatments have failed. ...
Researchers from the Arthritis Research UK Pain Centre at The University of Nottingham have discovered a new way to potentially block the chronic and often debilitating pain affecting osteoarthritis sufferers.