Glioblastoma (GBM) is the most invasive and devastating primary brain tumor with a median overall survival rate about 18 months with aggressive multimodality therapy. Its unique characteristics of heterogeneity, invasion, clonal populations maintaining stem cell-like cells and recurrence, have limited resp...
Glioblastoma is the most frequent and aggressive brain cancer due to its ability to escape the immune system. However, the way in which this tumor manages to induce this immune tolerance was not known in detail. A research published inPNAScarried out at the Instituto de Neurociencias UMH-CSIC,...
Glioblastoma (GBM)TherapyClinical trialsIn recent times, the intersection of nanotechnology and biomedical research has given rise to nanobiomedicine, a captivating realm that holds immense promise for revolutionizing diagnostic and therapeutic approaches in the field of cancer. This innovative fusion of ...
In addition to NF2 disease there could be potential benefit for other cancers with the same mutations, including mesothelioma (usually linked to exposure to asbestos), breastcancer, colorectal carcinoma, melanoma, glioblastoma and spontaneous schwannomas and meningiomas occurring independently of NF2. Sci...
Research on irradiation-induced transcription in glioblastomas can contribute to the understanding of radioresistance mechanisms. In this study, by using the total mRNA sequencing (RNA-seq) analysis, we assayed the global gene expression in a human glioma cell line U251 MG at various time points ...
Antitumor Potential of Antiepileptic Drugs in Human Glioblastoma: Pharmacological Targets and Clinical Benefits Glioblastoma (GBM) is characterized by fast-growing cells, genetic and phenotypic heterogeneity, and radio-chemo-therapy resistance, contributing to its di... M Stella,G Baiardi,S Pasquariello,...
Part 1 || Characterization of a New Human Glioblastoma Cell Line That Expresses Mutant P53 and Lacks Activation of the PDGF Pathway 来自 onAcademic 喜欢 0 阅读量: 19 作者: RA Gjerset,H Fakhrai,DL Shawler,S Turla,O Dorigo,A Grover-Bardwick,M Dan,SF Wen,H Collins,L Hong 展开 ...
Glioblastoma is fast-growing and hard to treat. Patients usually live 12 to 18 months afterdiagnosis. Even after many years of research, there are few options if the cancer returns after treatments. A kind of cell in the i...
Glioblastoma is a type of invasive malignant tumor due to the presence glioblastoma tumor stem cells, so separation of MSC mitochondria can be transferred to glioblastoma cells. Further analysis of mitochondria transfer cells can help determine the role of exogenous mitochondria in cell metabolism and ...
Scientists had earlier assumed glioblastoma tumors only arose fromglial cells, which support and protect the neurons and supply them with nutrients and oxygen. When stem cells were discovered within the brain, they were also implicated as being capable of leading tocancer cells. ...