The cause of psoriasis is unknown, although it appears to be an autoimmune disease with a genetic component to its aetiology. Past topical treatments such as emollients, coal tar and dithranol have been messy, cosmetically unacceptable or of low efficacy, while older systemic therapies have ...
psoriasis rheumatoid arthritis FURTHER INFORMATION Global Initiative on Obstructive Lung Disease World Bank World Health Organization Glossary EMPHYSEMA The destruction of the lung parenchyma by proteolytic enzymes (proteases). LUNG PARENCHYMA The part of the lungs beyond the airways (alveoli) at wh...
Several new classes of drug are targeted at signal-transduction pathways and transcription factors that regulate the expression of inflammatory genes and the immune mechanisms that underlie allergic inflammation. A major challenge is to develop drugs that are as effective as existing inhaled treatments an...
BACKGROUND: A calcipotriol (calcipotriene)/betamethasone dipropionate two-compound product has been shown to be efficacious for the treatment of psoriasis ... Cassano,Nicoletta,Miracapillo,... - 《Clinical Drug Investigation》 被引量: 19发表: 2006年 Expert recommendations: the use of the fixed co...
It is explicitly not our intention to compare novel treatments with their specific advantages and disadvantages with existing ones, because this is best done by experts in a therapeutic area. Similarly, we do not discuss drug pricing for novel treatments. Such discussion can only be meaningful base...
The drug, icotrokinra, is a once-daily pill whose efficacy has been demonstrated in patients with moderate to severe plaque psoriasis. Plaque psoriasis is a skin disease that causes dry, itchy patches of skin. Johnson & Johnson is working to develop new treatments because its current top-selli...
It will take some time and more research to better define when and how to make that switch; which patients would be the best candidates for the changeover; and how to manage the fact that the JAK inhibitors are not approved as ongoing, long-term treatments. “We don’t have answers for...
New treatments are changing the prospects for people with psoriasis according to Professor Griffiths. "The objective for treating psoriasis has been to reduce the visible symptoms," he said. "But new drugs are fast showing us that a realistic goal for all patients should be attaining clear skin ...
It has also been proved to be an effective therapy for moderate-to-severe plaque psoriasis. However, there is mounting evidence that etanercept can trigger new-onset or exacerbate pre-existing psoriasis.关键词: carbapenem antibiotics cytomegalovirus drug-induced hypersensitivity syndrome human herpesvirus ...
Psoriasis, a chronic skin condition that causes itchy, red, scaly patches, afflicts more than 8 million Americans and 125 million people worldwide. Small molecule-based drugs like steroids can penetrate the skin to treat the condition, but they can cause