The article reports that a new type of calcineurin inhibitor showing strong promise in a clinical trial could prove to be one of the safest and most effective therapies for plaque psoriasis. In a study of people aged 18 to 6...
The drug, icotrokinra, is a once-daily pill whose efficacy has been demonstrated in patients with moderate to severe plaque psoriasis. Plaque psoriasis is a skin disease that causes dry, itchy patches of skin. Johnson & Johnson is working to develop new treatments because its current top-selli...
The medications can also have side effects. Those include infections and other immune-related diseases, such as the skin condition psoriasis, said Dr. Giovanni Monteleone, the lead researcher on the new study and agastroenterologistat the University of Rome Tor Vergata, in Italy. The "advantage" ...
Jiang H, Myler H, Zeng JN, Mora J, Kolaitis G, Pillutla R. Perspectives on exploring hybrid LBA/LC-MS approach for clinical immunogenicity testing. Bioanalysis. 2019;11:1605–17. CAS PubMed Google Scholar Xu Y, Garofolo F, Musuku A. The exciting world of oligonucleotides: a multidisci...
(JAK1, JAK2, and JAK3) that signal your cells to make more inflammation. One study found that people who took a JAK inhibitor for just over 3 months were twice as likely to have a strong response as those who took a placebo, or fake pill. Two drugs, tofacitinib and upadacitinib, ...
antidiuretic, and prolongs bleeding time.4It has been evaluated in several human clinical studies as a treatment for idiopathic pulmonary hypertension.5,6In these studies, an aerosolized dose of 30 µg/day was effective, and doses as high as 150 µg/day for up to a year were well tole...
G-BA. Nutzenbewertungsverfahren zum Wirkstoff Ixekizumab (Neues Anwendungsgebiet: Plaque-Psoriasis bei Kindern und Jugendlichen ≥ 6 bis < 18 Jahre, Körpergewicht ≥ 25 kg) - Gemeinsamer Bundesausschuss. 2021. G-BA. Nutzenbewertungsverfahren zum Wirkstoff Caplacizumab (neues Anwendungsgebiet...
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Psoriatic arthritis. Psoriasis is known for causing itchy skin and rashes, but this autoimmune disease also harms joints. People with psoriatic arthritis usually experience skin problems before their joints become inflamed. This can cause permanent joint damage if untreated. ...
Researchers from Oregon Health & Science University and institutions across the country have identified a pill used to treat a common skin disease as an "incredibly promising" treatment for alcohol use disorder. Their study was recently published in theJournal of Clinical Investigation. ...