It is not the first time in pharmaceutical history that a class of drugs has been ignored, only to spur a gold rush when a successful medicine emerges. The arrival of Prozac (fluoxetine) in 1987 spawned many competitors, leading to the broad range of similar antidepressants available today. T...
New drugs called antibody-drug conjugates help patients with cancers that used to be beyond treatment
In pharmaceuticals, the 20th century was the era of the small molecule. The industry thrived by identifying a steady stream of relatively simple compoundsBusiness Insider
Mass balance is an important concept in pharmaceutical development, but it often proves challenging to assess accurately. This article explores the various methods by which mass balance can and should be measured, expressed, and evaluated in conjunction with degradation chemistry. Causes of mass-balance...
“help researchers design studies that will yield interpretable results that will be capable of supporting future drug applications,”according to Tiffany Farchione, director of the FDA’s Division of Psychiatry. A 60-day public comment period is open for interested parties to submit feedback on ...
and other milestones relating to Zepbound and reflectsLilly's current belief and expectations. However, as with any pharmaceutical product, there are substantial risks and uncertainties in the process of drug research, development, and commercialization. Among other things, there can be ...
Comparison of Resaerch Spending on New Drug Approvals by the National Institutes of Health vs the Pharmaceutical Industry, 2010-2019. JAMA Health Forum. 2023;4(4):e2305112. 2. Frank RG, Hannick K. 5 things to understand about pharmaceutical R&D. USC-Brookings Schaeffer on Health Policy. ...
A pharmaceutical company claims that its new drug reduces systolic blood pressure. The systolic blood pressure(in millimeters of mercury)for nine patients before taking the new drug and2 hours after taking the drug are shown in the table be...
Pharmaceutical companies have been referring to the 2016 study of the Tufts University to justify the costs of cancer drugs, asreportedon ScienceDirect: “We have conducted the fourth in a series of comprehensive compound-based analyses of the costs of new drug development. In the last study we...
Wegovy, made by Danish drugmaker Novo Nordisk, is the first in what is shaping up to be a new generation of obesity treatments, which use a hormone to regulate appetite. (The name is the result of a nebulous bureaucratic process involving pharmaceutical regulators and the company’s marketers...