British Journal of Cancer (2011) 105, S5 – S10 & 2011 Cancer Research UK All rights reserved 0007 – 0920/11 www.bjcancer.com Full Paper New pathways of care for cancer survivors: adding the numbers J Maher1,2 and H McConnell*,3 1Mount Vernon Cancer Centre, Mount Vernon Hospital, ...
and they are an attractive therapeutic target. While skeletal abnormalities are commonly seen in children with acute lymphoblastic leukemia (ALL) prior to initiating osteotoxic therapy, little is known about the alterations to the bone marrow microenvironment during leukemogenesis. Therefore, in this...
Chronic daily RIC is a promising therapy for chronic neurological conditions, such as white matter disease and vascular cognitive impairment Abstract Remote ischaemic conditioning (RIC) triggers endogenous protective pathways in distant organs such as the kidney, heart and brain, and represents an exciti...
Centre for Old Age Psychiatry Research, Innlandet Hospital Trust, Ottestad, Norway Sverre Bergh Department of Geriatric Medicine, Landspitali University Hospital, Reykjavik, Iceland Sigurbjorn Bjornsson, Palmi V. Jonsson & Jon Snaedal Geriatric Department, Oslo University Hospital, Oslo, Norway Anne Br...
Examples of coherent beams produced by cancer cells. Enlarged and slightly contrasted parts of fingertip coronas are shown next to the raw BHT-grams. A – gastrointestinal cancer, ongoing radiation therapy; B – non-treated renal cancer with spreading metastasis. White arrows point to the scal...
Myeloid cells as effector cells for monoclonal antibody therapy of cancer. Methods 65, 28–37 (2014). Article CAS PubMed Google Scholar Futosi, K., Fodor, S. & Mocsai, A. Neutrophil cell surface receptors and their intracellular signal transduction pathways. Int. Immunopharmacol. 17, 638–...
Targeting multiple signaling pathways: the new approach to acute myeloid leukemia therapy Jenna L. Carter, Katie Hege, Jay Yang, Hasini A. Kalpage, Yongwei Su, Holly Edwards, Maik Hüttemann, Jeffrey W. Taub & Yubin Ge Signal Transduction and Targeted Therapy volume 5, Article ...
Complex Dilemmas in Group Therapy: Pathways to Resolution (2nd ed.). Edited by Lise Motherwell and Joseph J. Shay . New York, NY : Routledge , 2014 , 224 pp., paperback $43.95; hard cover $165.00 .doi:10.1521/ijgp.2015.65.1.152
Combination therapy with SGLT-2is and MRAs also need to be better explored to understand if benefits are additive. Additional clinical and real-world studies are warranted to elucidate best clinical practices. It is important to emphasize the intention of this review, along with its limitations. ...
Heldin also points at the general advantage of targeting signalling pathways incancer therapy. "In theory, the same medicine could be used to treat different tumours because they have the same mutations," he notes. However, since tumours differ greatly between individual patients, "we have to de...