New methods of administering old drugs: IV infusion of mercaptopurineIn order to maximize an anti-neoplastic agent's activity it is essential to consider the drug's pharmacokinetics. The importance of route and schedule of administration has been well exemplified by......
A Herxheimer,MB Douglas - 《Journal of Pharmacy & Pharmacology》 被引量: 0发表: 2011年 629. A chocolate treat in store for test animals: Herxheimer, A. & Douglas, M. B. (1963). A new method of administering drugs by mouth to animals. J. Pharm... No abstract is available for thi...
A method for treating non-infectious inflammatory vulvovaginitis comprises administering to a vulvovaginal surface a pharmaceutical composition that comprises clindamycin in an amount of about 125 mg to about 400 mg per unit dose of the ... LEVINSON R. SAUL,CUCA ROBERT C.,BORTZ JONATHAN - WO ...
METHOD-OF-USE PATENT (MOU). A patent containing one or more claims directed to a method of use (for example, a method of treating disease X, comprising administering a therapeutically effective amount of product Y to a subject in need thereof). The exclusionary right is limited to the parti...
of the viruses in combination with other therapies, such as immune checkpoint inhibitors, to enhance cancer treatment outcomes. The research is particularly active in conditions where tumors are accessible for direct injection, a method commonly deployed for administering these therapies. There are also...
As a partner of MindRank, Medicilon provides API process development and preparation R&D services for MDR-001. Recommend:Medicilon congratulates MindRank's GLP-1RA small molecule oral drug for successfully administering the first subject in clinical phase I ...
In contrast to most fields of medicine, progress to discover and develop new and improved psychiatric drugs has been slow and disappointing. The vast majority of currently prescribed drugs to treat schizophrenia, mood and anxiety disorders are arguably no more effective than the first generation of ...
Drugs targeting S1PR1–5 can modulate the egress of lymphocytes from the lymph nodes, reducing their availability to contribute to inflammation in the gut. In addition, modulation of S1P signaling may help maintain the integrity of the intestinal barrier. Ozanimod and etrasimod, both S1P modulators...
potentially incorporating innovative methodologies for administering RSS interventions. Furthermore, a control group was not incorporated within the present study design and may be beneficial in future research. It may also be worthwhile to consider examining RSS training programs and the effects on varyin...
It is, however, possible for a skilled patent drafter to construct a compound claim for a metabolite to avoid anticipation by claiming it in its pure, isolated form, as part of a pharmaceutical formulation, or by claiming a novel method of administering the pure, isolated metabolite or its ...