This paper reviews asthma assessment in primary care and describes the pathophysiology, clinical characteristics and new targeted treatments available for patients with severe eosinophilic asthma. Methods: A non-systematic PubMed literature search was conducted and articles, primarily from the last 5 ...
D. Animal models for COPD. Chest 117, 223S–227S (2000). Article CAS PubMed Google Scholar Hansel, T. T. & Barnes, P. J. New Drugs for Asthma and COPD (Karger, Basel, 2001).This book reviews all of the new approaches to COPD therapy that are discussed in this review in more...
Patients were hospitalized and received supplemental oxygen, treatment for an acute asthma exacerbation with systemic corticosteroids, high dose inhalation therapy. These therapeutic interventions subsequently led to a good outcome for the mother and newborn in both cases. Conclusions: New onset asthma ...
"These are the patients that turn up in [the] emergency room with really bad asthma attacks and have the most morbidity from their disease," Dr Arron toldMedscape Medical News. "This is the target population for these new biologic therapies." The new therapies will cost more, but treat th...
Despite dramatic advances in our understanding of the pathogenesis and course of disease in the relatively short timeframe since the discovery and first description of eosinophilic esophagitis (EoE) less than three decades ago, many open questions remain to be elucidated. For instance, we will need...
Sensitivity and specificity for ABPM diagnosis were examined using data from cases with pathological ABPM (n = 79), fungus-negative mucus plugs (n = 37), chronic eosinophilic pneumonia (n = 64), severe asthma with Aspergillus sensitization (n = 26), and chronic pulmonary aspergillosis (n =...
Eosinophil ETosis and DNA traps: a new look at eosinophilic inflammation. Curr Allergy Asthma Rep 2016;16:54. PUBMED | CROSSREF... Tokunaga,Takahiro,Weller,... - 《Current Allergy & Asthma Reports》 被引量: 12发表: 2016年 TREATMENT OF ACUTE ASTHMA: A New Look at the Old and at the...
(Fig. 6E). Among the top-ranking pathway, the RAGE pathway was regarded as the focus of attention, as RAGE signaling are involved in dendritic cell-T-cell cross-talk [46], and plays a central role in the pathogenesis of eosinophilic asthma [47]. The members of the NF-κB family are ...
“This paper is about fear. Systems pharmacology model enables us to explain that one shouldn’t be afraid of high blood eosinophilic count while taking anti-Interleukin 13 medication. Moreover we managed to provide mathematical ar...
Besides those mentioned above, CAR-Tregs have been used for the treatment of other diseases, such as hemophilia A [73,74], vitiligo [75], inflammatory bowel disease [46,76], asthma [77,78], cardiovascular diseases [79] and senescence-associated pathologies [80]. They have also been employe...