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2021). EA draws inspiration from natural evolutionary processes, with genetic algorithms (GA) (Holland 1992) and differential evolution (DE) (Storn and Price 1997) as two of its most representative members. These algorithms are rooted in Darwin's theory of evolution. On the other hand, PhA ...
β2-integrins are adhesion- and mechanoreceptors expressed exclusively on leukocytes. They mediate diverse functions in immunity and are of fundamental importance in processes such as leukocyte trafficking, phagocytosis, T cell and B cell activation and.
13. Bridgeman JS, Hawkins RE, Bagley S, Blaylock M, Holland M, Gilham DE. The optimal antigen response of chimeric antigen receptors harboring the CD3ζ transmembrane domain is dependent upon incorporation of the receptor into the endogenous TCR/CD3 complex. The Journal of Immunology. 2010;184...
8 Holland IB, Blight MA: ABC-ATPases, adaptable energy generators fuelling transmembrane movement of a variety of molecules in organisms from bacteria to humans. J Mol Biol 1999; 293: 381 – 399. 9 Dawson RJ, Locher KP: Structure of a bacterial multidrug ABC transporter. Nature 2006; 443...
International Journal of Molecular Sciences Review New Therapeutic Implications of Endothelial Nitric Oxide Synthase (eNOS) Function/Dysfunction in Cardiovascular Disease Andreas Daiber 1,2,* , Ning Xia 3, Sebastian Steven 1, Matthias Oelze 1, Alina Hanf 1, Swenja Kröller-Schön 1, Thomas ...
(Holland Scientific INc., Lincoln, NE, USA) both based on multispectral sensors which supply information for vegetation (e.g., NDVI or plant height) and cropping indices calculations, OptRx (AgLeader Tech., Ames, IA, USA) providing state-of-the art crop sensing technology in grains and ...
Promising activity has been demonstrated in patients with B-lineage ALL, specifically in MRD eradication [118]-[120]. The first phase 1 trial of blinatumomab as single agent given as continuous intravenous infusion in NHL began in 2004. The initial cohort of 38 patients had R/R B-cell NHL...
Promising activity has been demonstrated in patients with B-lineage ALL, specifically in MRD eradication [118]-[120]. The first phase 1 trial of blinatumomab as single agent given as continuous intravenous infusion in NHL began in 2004. The initial cohort of 38 patients had R/R B-cell NHL...
Tumor immunotherapy exerts its anti-tumor effects by stimulating and enhancing immune responses of the body. It has become another important modality of anti-tumor therapy with significant clinical efficacy and advantages compared to chemotherapy, radiot