* Study selection and analysis: Randomised controlled trials, reporting on relapse rates and of [greater than or equal to]6 months' duration, comparing new generation antipsychotic drugs with placebo or conventional antipsychotics in people with schizophrenia or schizophrenia-like psychoses. Data were ...
QT prolongation is a heart rhythm condition that impacts the lives of many people and when severe can be life-threatening. QT prolongation has been linked to variations in several genes, but it can also arise in the course of treatments with medications such as certain antipsychotics and antidepr...
the evidence also supports the effectiveness of long-acting injections (LAIs) or depots of antipsychotics regarding their relapse-preventing properties. When a LAI formulation of risperidone was launched as the first second-generation depot, there was a renaissance of interest in ...
The atypical antipsychotics are a new class of agents with great promise for use in the elderly because of their reduced propensity to cause acute extrapyr
Metabolic side effects of new generation antipsychotics With the introduction of atypical antipsychotics, a promising new erain the treatment of schizophrenia and psychotic disorders has begun.These drugs effect... L Mete,PÇ Ünsal - Bulletin of Clinical Psychopharmacology - Klinik Psikofarmakoloji ...
Glutamatergic drugs for schizophrenia: a systematic review and meta-analysis. Schizophr. Res. 72, 225–234 (2005). Article Google Scholar Goff, D.C. et al. A six-month, placebo-controlled trial of D-cycloserine co-administered with conventional antipsychotics in schizophrenia patients. ...
,... - 《Cns Drugs》 被引量: 221发表: 2002年 Risperidone versus other atypical antipsychotics for schizophrenia In many countries of the industrialised world second-generation ("atypical") antipsychotics (SGAs) have become the first line drug treatment for people wit... K Komossa,C Rummel-...
However, with wide spread use of new generation antipsychotics in recent years particularly in the treatment of patients with schizophrenia researchers reported that prevalence of type II diabetes mellitus in these patients has been increased or patients' glucose and/or lipid proles have been worsened....
Newpsychotropicdrugsintroducedinclinicalpracticeinrecentyearsincludenewantidepressants,suchasselectiveserotoninreuptakeinhibitors(SSRI)and‘thirdgeneration’antidepressants,andatypicalantipsychotics,i.e.clozapine,risperidone,olanzapine,quetiapine,ziprasidoneandamisulpride.TheseagentsareextensivelymetabolizedintheliverbycytochromeP450...
The atypical antipsychotics are a new class of agents with great promise for use in the elderly because of their reduced propensity to cause acute extrapyramidal adverse effects. Treatment of older patients with these agents, however, needs to take into consideration age-related changes in pharmacokin...