The pro-apoptotic Bax and Bak proteins are considered central to apoptosis, yet apoptosis occurs in their absence. Here, we asked whether the mitochondrial protein VDAC1 mediates apoptosis independently of Bax/Bak. Upon screening a fungal secondary metabolite library for compounds inducing apoptosis in...
An important mechanism for insect pest control should be the use of fungal entomopathogens. Even though these organisms have been studied for more than 100 y, their effective use in the field remains elusive. Recently, however, it has been discovered that many of these entomopathogenic fungi play...
have an infection that does not go away or that keeps coming back. have TB or have been in close contact with someone with TB. have recently received or are scheduled to receive an immunization (vaccine). Medicines that intera...
Did anyone else have that on their 2024 bingo card? Photo by CDC on Unsplash Me neither. But according to theCDC, there is a fungal infection that is spreading across the country and already has a grip on New Jersey. Candid Auris Is Spreading Across The Country ...
06 February 2024 A Correction to this paper has been published: Abbreviations C.acnes: Cutibacteriumacnes EVs: Extracellular vesicles PBS: Phosphate-buffered saline SN: Supernatant TEM: Transmission electron microscopy NTA: Nanoparticle tracking analysis ...
The development of new drugs to fight a common fungal pathogen which kills half a million people globally each year is a step closer thanks to a University of Queensland-led study.
The excessive use of antifungal agents, compounded by the shortage of new drugs being introduced into the market, is causing the accumulation of multi-resistance phenotypes in many fungal strains. Consequently, new alternative molecules to conventional a
The divergent cytoplasmic deacetylase FolSir2 was biochemically characterized, which is contributing to fungal virulence. Based on this, a total of 1752 acetylated sites in 897 proteins were identified inFolvia LC–MS/MS analysis. Further analyses of the quantitative acetylome revealed that 115 protein...
For a long time, applicants with HIV were not eligible for occupational disability insurance as the infection led to severe immunodeficiency and consequently death in almost all cases.
Onychomycosis, or tinea unguium, is a fungal infection of the nail. Onychomycosis can result in discoloration of the nail, onycholysis (nail separation from the nail bed), and nail plate thickening. Onychomycosis ...