in epilepsy genetics and the development of novel disease models, drug screening technologies and innovative therapeutic modalities over the past 10 years, more than 200 novel epilepsy therapies are currently in the preclinical or clinical pipeline, including many treatments that act by new mechanisms....
New epilepsy treatmentsThe article offers information on the suggested epilepsy treatments from the National Institute for Health and Clinical Excellence (NICE) of Great Britain which include buccal midazolam, rectal diazepam, and intravenous lorazepam.Pulse...
Epilepsy ++ − + Movement disorder + − ± Myopathy − + + Biochemical features CNS Cr deficiency↑ GAA (P, U, CSF) CNS Cr deficiency↓ GAA (P, U, CSF) CNS Cr deficiency↑ Cr/Crn (U) Treatment available High Cr doses (400 mg/kg/day)Orn supplementationArg restrictionPre-symptoma...
All other treatments will be allowed. Provisions for post-trial care Any patients who suffer harm from trial participation will be covered by the Japanese public healthcare system. Clinical assessments On enrollment in this trial, clinical research physicians will obtain information from the patients ...
Neurology. Drugs in the neurology space were second on the list of top drug categories, with 29 candidates in the pipeline for 2020. These include new therapies for common conditions (migraine, Parkinson's disease, epilepsy) and advanced therapies for rare conditions (spinal muscular atrophy, neur...
conference, we will be continuing with debates as well as adhering to the format of the previous conferences which are designed to provide an in-depth progress report on new antiepileptic drugs in various stages of development, as well as to present new findings on second-generation treatments. ...
A new chapter opens in anti-inflammatory treatments: the antidepressant bupropion lowers production of tumor necrosis factor-alpha and interferon-gamma in mice. Int Immunopharmacol. 2006;6:903–7. CAS PubMed Google Scholar Tsai JH, Kuo CH, Yang P, Cheng KH, Wang PW, Chen CC, et al. ...
That's how Hofmann joined a long line of epilepsy patients who've helped scientists reveal basic secrets of the brain—knowledge that could pay off in better ways to measure consciousness in brain-injury patients and new treatments for a variety of diseases. Research volunteers such as Ruth Nall...
In the field of epilepsy, the identification of more than 100 causative genes provides the enticing possibility of treatments targeted to specific disease etiologies. These conditions include classical examples, such as the use of vitamin B6 in antiquitin deficiency or the ketogenic diet in GLUT1 ...
helpful resources and encourage them to seek sustained treatment. Developing targeted CUD treatments for pregnant populations is crucial due to increasing CUD rates,