New drugs for schizophrenia in FDA pipeline.(Originated from Knight-Ridder Newspapers)Harkness, Richard
The Promise of New Drugs for Schizophrenia Treatment To present aspects of preclinical and clinical pharmacology of new antipsychotic drugs and to emphasize those preclinical drug characteristics which might predict desirable clinical actions. Review of the relevant literature and publicly... Tamminga,Ca ...
In contrast to most fields of medicine, progress to discover and develop new and improved psychiatric drugs has been slow and disappointing. The vast majority of currently prescribed drugs to treat schizophrenia, mood and anxiety disorders are arguably no more effective than the first generation of ...
The use of novel drugs such as inhaled loxapine (LOXi) for schizophrenia and the off-label use of substances such as sodium nitroprusside (NIT) for the management of mental disorders require further investigation. We aimed to evaluate the efficacy and safety of LOXi and NIT for the treatment...
Since a schizophrenia drug, the first in decades with an innovative mechanism of action, gainedUS regulatory approval in September, some researchers have proclaimed anew era for psychiatric medicine. About half a dozen similar drugs — for schizophrenia, Alzheimer’s disease and other conditions involv...
Research on alternative targets for antipsychotic drugs, beyond the dopamine D2 receptor, has expanded the potential treatment options for schizophrenia and gives an important way to address the challenge of refractory schizophrenia. This article aims to provide a comprehensive overview of th...
María José, GuerreroItsaso, HormaecheMaría, UribarriJulie, MasseJosé María, Palacios. Exocytotic Machinery as a Target for the Development of New Drugs for Schizophrenia. 2012:, 375-408. /María JoséGuerrero, ItsasoHormaeche, MaríaUribarri, JulieMasse, José MaríaPalacios. Exocytotic ...
Alzheimer's disease (AD) is the leading cause of dementia, presenting a significant unmet medical need worldwide. The pathogenesis of AD involves various pathophysiological events, including the accumulation of amyloid and tau, neuro-inflammation, and ne
Schizophrenia is a devastating mental disease that affects the human population worldwide with an incidence of about 1%. Over the last decades basic and clinical research has considerably increased our understanding of the pathophysiology of schizophrenia, as well as the mechanism of action of antipsych...
While 16 may be to young to use drugs and drink in mass amounts because our brains our still developing, we have feelings. It’s people like you who have made me to afraid to come out for 3 years, and have scared me into believing I don’t belong. Thank you, you are the reason...