The past several years have seen an explosion in the number of candidate therapies for Parkinson's disease (PD). These include new formulations and routes of delivery of dopaminergic agents aimed at reducing off time and dyskinesia, rescue therapies designed to provide rapid and predictable ...
Vancouver, BC—New pharmaceutical strategies in the treatment of Parkinson disease (PD) are emerging as basic and clinical research burgeons throughout the neurological community worldwide. Discoveries made by Viennese investigator Oleh Hornykiewicz, MD, in the 1960s—that depletion of dopamine in ...
The new study, published Sept. 1 inScience, found that the compounds appear to dampen activity in a gene implicated in Parkinson's disease. "We think this is an exciting potential pathway to developing new treatments for Parkinson's," said senior researcher Dr. Clemens Scherzer. He's a neur...
The longevity of adult-born neurons argues for probable functional integration that can be used for therapeutic purposes in patients with striatal disorders such as Huntington’s disease, Parkinson’s disease (PD), Alzheimer’s disease (AD) and other disorders [132]. Overall, in adult striatal ...
Polyphenols and other antioxidants have successfully influenced the health status of patients diagnosed with a variety of chronic conditions, such as cardiovascular disease [61,62], cancer [63,64], endometriosis [65], osteoarthritis [66,67], Parkinson’s [68], and Alzheimer’s disease [69,70]...
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The pharmacology of Parkinson's disease: Basic aspects and recent advances Basic aspects and recent advances in the understanding of the pharmacological mechanism of action of the clinically most used antiparkinson drugs are revie... M.,Da,Prada,... - 《Cellular & Molecular Life Sciences》 被引...
Parkinson’s schizophrenia Tourette’s syndrome [Many high-achievers take “smart drugs.” But does that make them a good idea? Know the risks and benefits.] NUTRITION FOR THE MIND/BODY CONNECTION It’s almost impossible to live a lifestyle that provides all the nutrients needed for good brai...
A small molecule 20C fromGastrodia elatainhibits α-synuclein aggregation and prevents progression of Parkinson’s disease ArticleOpen access06 September 2023 Introduction Alzheimer’s disease (AD) is the most common neurodegenerative disease1, with a prevalence of more than 50 million cases worldwide ...
Therapeutic role of 5-HT1A receptors in the treatment of schizophrenia and Parkinson's disease CNS Neurosci. Ther., 17 (2011), pp. 58-65 https://doi.org/10.1111/j.1755-5949.2010.00211.x CrossrefView in ScopusGoogle Scholar [2] F. Artigas, A. Bortolozzi, P. Celada Can we increase ...