Although these drugs are effective in osteoporosis treatment, their use is limited by their side-effects and low-adherence. The aim of this review article was to compare efficacy of new drugs for osteoporosis currently in phase 2 and 3 clinical trials. After reviewing 57 articles available on ...
WNT7B, that stimulates new bone growth (shown in pink on the right). The protein could become a target for new drugs to treat osteoporosis and other conditions related to bone loss. Credit: Washington University
Osteoporosis has become global health issue due to the longer life-cycle and increased percentage of older people in population. The great improvement was done in the treatment of postmenopausal osteoporosis. By the mechanism of action, drugs for osteoporosis treatment are antiresorptives and osteoanab...
Using a compound derived from red sage, UBC researchers have found a way to selectively block an enzyme called Cathepsin K (CatK), which plays a major role in the breakdown of collagen in bones during osteoporosis. The development of osteoporosis drugs by pharmaceutical companies has focused heav...
Denosumab: A New Treatment for Osteoporosis 来自 ProQuest 喜欢 0 阅读量: 23 作者: L Speroff 摘要: The article presents a commentary addressing a study on the effectiveness of denosaumab, a human monoclonal antibody, to treat osteoporosis in postmenopausal women. It is inferred that the ...
A new model, described today in eLife, may help improve outcomes for patients with postmenopausal osteoporosis and reduce the risks of side effects by helping physicians build more personalized treatment regimes.
Besides classical agents, such as bisphosphonates a number of new drugs have been introduced or are currently being explored including the RANKL inhibitor denosumab or the cathepsin K inhibitor odanacatib. The aim of this talk is to provide an overview about new mechanistic, diagnostic and clinical ...
The prospect of probiotics in osteoporosis therapy Fecal microbiota transplantation may not be an effective option for the treatment of OP due to the presence of harmful bacteria within the transplant material. Studies have shown that the therapeutic effects of FMT for IBD are also inconsistent.36The...
encompassing substantial progress in physical rehabilitation and surgical procedures, management of hearing, dental and pulmonary abnormalities, as well as drugs, such as bisphosphonates and recombinant human growth hormone. Novel treatments using cell therapy or new drug regimens hold promise for the futur...
(1997). GREES recommendations for the registration of new drugs in the prevention and treatment of osteoporosis. Calcif Tissue Int 60: 488. View Article... JY Reginster,J Compston - 《Calcified Tissue International》 被引量: 26发表: 1997年 GREES recommendations for the registration of new dru...