(1997). The green pharmacy: New discoveries in herbal remedies for common diseases and conditions from the world's foremost authority on healing herbs. Pennsylvania: Rodale press.Duke JA. 1997. The Green Pharmacy: New discoveries in herbal remedies for common diseases and conditions from the ...
In the basal state, Nrf2 is mostly found in the cytoplasm of cells, bound to Keap1. Nrf2 relies on proteasomal degradation to maintain low intracellular levels, which is mediated by Keap1. Keap1, in association with CUL3 and Rbx1, forms a functional E3 ubiquitin ligase that ubiquitinates Nr...
The discoveries of a new antitumor agent (LY32262) (N-[2,4-dichlorobenzoyl]phenylsulfonamide) and a close analog (LY33169) are described. For this discover... TH Corbett,K White,L Polin,... - 《Invest New Drugs》 被引量: 59发表: 2003年 Status of safety pharmacology in the pharmace...
Investigational New Drugs provides the fastest possible publication of new discoveries and results for the whole community of scientists developing anticancer agents. Each issue contains original articles dealing with anticancer drug development. Other sections are devoted to invited review articles and ...
Consequently, we anticipate that a study with a larger sample size will validate and broaden our discoveries. Moreover, the prognostic and follow-up utility of these biomarkers should be further investigated. Conclusion In conclusion, this study explored that AKT3, GSK-3β, and hsa-miR-16a-5p...
Using advanced modeling techniques, these computational technologies can enhance efficiency and accuracy, handle complex data, and facilitate novel discoveries within minutes. Furthermore, these technologies offer several advantages over conventional statistics. They allow for pattern recognition from complex ...
Huntington disease is a rare, inherited disease that causes a progressive breakdown of nerve cells in the brain. This disease gets worse over time and can affect movement, cognition, and mental health. The study notes that in the recent discoveries, scientists found that ribonucleic acid (RNA) ...
Heat shock protein 90 (Hsp90) is an ATP dependent molecular chaperone deeply involved in the complex network of cellular signaling governing some key functions, such as cell proliferation and survival, invasion and angiogenesis. Over the past years the N
Faculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran 6 Regional Centre of Advanced Technologies and Materials, Palacký University in Olomouc, Šlechtitelů 27, 783 71 Olomouc, Czech Republic ...
"These new discoveries highlight the major role that high blood pressure plays in developing the disease and shed light on how this occurs and might be prevented in the future. At present, the most important thing you can do to lower your risk of the disease is to keep your blood pressure...