New Developments in Medicinal ChemistryVanessa Leiria CampoValquiria AragaoLeoneti
In the case of IDDM, genetic analysis has demonstrated the possible involvement of more than 20 loci (chromosome locations), which contribute to its inheritance. Although nearly all of the genes involved still have to be isolated and their structure and function determined, a genetic approach ...
Histone deacetylase inhibitors in cancer therapy: latest developments, trends and medicinal chemistry perspective. Regulation of gene expression is mediated by several mechanisms such as DNA methylation, ATP-dependent chromatin remodeling, and post-translational modific... Konstantin V. Balakin, Yan A. ...
2023, European Journal of Medicinal Chemistry Show abstract Coumarin thiazoles as unique structural skeleton of potential antimicrobial agents 2022, Bioorganic Chemistry Citation Excerpt : Bacteria in the biofilm have strong drug resistance and the ability to resist the effects of the body's immune syst...
In contrast to most fields of medicine, progress to discover and develop new and improved psychiatric drugs has been slow and disappointing. The vast majority of currently prescribed drugs to treat schizophrenia, mood and anxiety disorders are arguably no more effective than the first generation of ...
- Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents 被引量: 32发表: 2003年 Latest developments in allergic rhinitis in Allergy for clinicians and researchers Research efforts in allergic rhinitis have always been intense. Over the past 3years, numerous breakthroughs in basic ...
This review covers recent developments in medicinal chemistry of natural and synthetic proteasome inhibitors. Advances in non-covalent inhibitors that have no reactive group will be highlighted as they should minimize side-effects. New structures and new modes of action have been recently identified ...
2023, European Journal of Medicinal Chemistry Show abstract Emerging impact of triazoles as anti-tubercular agent 2022, European Journal of Medicinal Chemistry Show abstract Coumarin–benzimidazole hybrids: A review of developments in medicinal chemistry 2022, European Journal of Medicinal Chemistry Show ab...
We also noted new developments in tetracycline chemistry70 and still more structural information is being reported on this class of antibiotics.216 The clinical progression of second-generation oxazolidinones into phase II studies was also mentioned.74–80 Achaogen is working to bring forward new ...
Recent developments in the design of anti-depressive therapies: targeting the serotonin transporter. The serotonin transporter protein (SERT) has been the target for the development of several modern antidepressants with an objective of achieving selectivi... S. G. Butler, M. J. Meegan - 《...