Mangia S, Tkac I, Gruetter R, van de Moortele P-F, Maraviglia B, Ug˘urbil K. Sustained neuronal activation raises oxidative metabolism to a new steady-state level: evidence from 1H NMR spectroscopy in the human visual cortex. J Cereb Blood Flow Metab 2007;27: 1055-1063....
while others are essential for multiple cancer characteristics. For instance, the Myc–Max and KRAS/PDE PPIs are involved in evading growth suppression and cell death, as well as promoting genomic instability and altered metabolism.238Consequently, targeting certain critical PPIs may disrupt multiple...
The status of copper metabolism-related genes and proteins, such as the expression levels of FDX1 and DLAT, could serve as predictive markers for the efficacy of cuproptosis-inducing therapy. Alterations in the expression or function of these proteins might indicate the cellular copper status and ...
In a study of the use of NBS in inborn errors of metabolism, rates of detection of 31 disorders including FAODs were examined.11 Of 57 patients with inborn errors of metabolism identified following the introduction of NBS, 15 were diagnosed clinically, and 7 of these were negative on NBS. ...
More specifically, new data on the mode of action and metabolism of neonicotinoids and fipronil, and their toxicity to invertebrates and vertebrates, were obtained. We included the newly detected synergistic effects and/or interactions of these systemic insecticides with other insecticides, fungicides, ...
Glycolytic reprogramming is one of the most important features of cancer and plays an integral role in the progression of cancer. In cancer cells, changes in glucose metabolism meet the needs of self-proliferation, angiogenesis and lymphangiogenesis, met
While the critical role of copper metabolism and homeostasis in safeguarding cellular integrity is well documented, the complexity of the dual role of copper — as both a vital nutrient and a potential cellular toxin—underscores the necessity for a nuanced understanding of its metabolic pathways. Th...
As I mentioned in my video post, teenagers in their late teen years that are player high school sports for example have much different requirements than older athletes due to metabolism, energy expenditure and hormonal levels. The supplement companies try to make money (it’s a billion dollar ...
Ferroptosis is a distinctive process of cellular demise that is linked to amino acid metabolism, lipid oxidation, and iron oxidation. The ferroptosis cascade genes, which are closely associated with the onset of lung diseases, are among the regulatory ta
L. et al. Effects of the BET-inhibitor, RVX-208 on the HDL lipidome and glucose metabolism in individuals with prediabetes: a randomized controlled trial. Metabolism 65, 904–914 (2016). CAS PubMed Google Scholar Ghosh, G. C., Bhadra, R., Ghosh, R. K., Banerjee, K. & Gupta, ...