The FDA's withdrawal of bevaci-zumab plus chemotherapy for thetreatment of metastatic breast cancer reflects not only the disappointing results of bevacizumab but also differences in opinion regarding the value of antiangio- genic therapy for breast cancer in general, according to experts."What ...
J. Harrison Howard, M.D., praised the USA Health Mitchell Cancer Institute's multidisciplinary clinic that focuses on melanoma. Published May 17th, 2023 By Carol McPhail cmcphail@health.southalabama.edu Treatment for melanoma, the most serious form of skin cancer, continues to evolve and improv...
for personalized cancer treatment to be effective, the patient’s melanoma must carry the BRAF mutation targeted by these medications (Table 1).3 Used in combination, BRAF and MEK inhibitors are first-line therapy when the BRAF mutation is present, according to the National Comprehensive Cancer Ne...
The study showed that the new skin patch could efficiently deliver medication in one minute to attack cells of melanoma, a deadly form of skin cancer. Using chicken ovalbumin as a model antigen, the researchers vaccinated mice with their pain-free microneedle patches, and compared the results wit...
In studies of mice with melanoma and breast tumors, the researchers showed that this treatment eliminated tumors completely in 40 percent of the mice. Furthermore, when the researchers injected cancer cells into these same mice several months later, their T cells recognized them and destroyed them...
SYDNEY, Aug. 17 (Xinhua) -- Australian scientists said they have found a way to help dermatologists better determine a patient’s risk of developing melanoma, pointing to improved understanding and treatment of the major skin cancer. The team from the University of Queensland uncovered the specif...
Researchers are also pushing the boundaries with checkpoint inhibitors, exploring new combinations and formulations to tackle resistance in tough-to-treat cancers like metastatic melanoma and ovarian cancer, and improving accessibility. Research Advancements for Rare Cancers Aside from these headline-making ...
10-13 It's not clear whether neoadjuvant immunotherapy will be effective for cancers without a strong immune component; however, it's evident that for melanoma, neoadjuvant therapy has shown significant benefit and the potential to change cancer treatment.1 REFERENCES 1. Long GV, Menzies AM...
The team from the Cancer Signaling Laboratory (ULiège) has just made a very interesting discovery in this field. "Thanks to the analysis of the data collected, we were able to observe that the adaptation of melanoma cells to targeted therapy was associated with a reprogramming ofprotein synthes...
In summary, McArthur says, "We anticipate that the combination of a BRAF and MEK inhibitor will become a new standard treatment for advanced BRAF-mutant melanoma. The data lay the foundation for the addition of treatments either in sequence or in further combination to obtain even better results...