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The process by which CTCs detach from the primary tumor and survive in the circulation.aTumor cells detach from the primary tumor. In the primary tumor, tumor cells will undergo epithelial-mesenchymal transition (EMT) triggered by some factors such as TGF-β, making them transition from the epi...
5.3. mTOR Complex (mTORC) mTOR, a serine/threonine kinase that forms two complexes, mTOR1 and mTOR2, is involved in a variety of cellular processes, such as the regulation of glucose metabolism, cell growth, energy balance and viability [133,134]. Rapamycin is a bacterial ma...
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Moreover, the health and economic balance burdened by the influenza seasonal epidemics constitutes an additional issue for humans. In fact, both epidemics and pandemics can only be definitely defeated by an universal vaccine. Unfortunately, to date, the approaches adopted to reach this main goal ...