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This heightened activity indicates the importance of PPP in meeting the needs of cancer cells for ribonucleotide synthesis and maintaining proper redox balance. As the rate-limiting enzyme in PPP, glucose-6-phosphate dehydrogenase (G6PD) has been the most studied one in HCC. G6PD has been ...
The quenching step is essential for the final mechanical properties and is required to balance two contradictory effects, namely, the quench-induced coarse precipitation with sizes of approximately 100 nm and the residual stress resulting from thermal gradients formed during quenching. Residual stress is...
Notch signaling controls the balance of ciliated and secretory cell fates in developing airways. Development 2009, 136, 2297–2307. [Google Scholar] [CrossRef] [Green Version] Ma, L.; Quigley, I.; Omran, H.; Kintner, C. Multicilin drives centriole biogenesis via E2f proteins. Genes Dev....