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but drug absorption and metabolism are influenced by gut microbes, and there are serious adverse effects of the drugs, such as bleeding due to the antiplatelet effects of excess aspirin. Further studies on the balance between drug efficacy, circulating bioavailability, and adverse drug effects by gu...
& Xu, H. Tuning of peptide assembly through force balance adjustment. J. Colloid Interface Sci. 407, 287–295 (2013). Article CAS PubMed Google Scholar Smadbeck, J. et al. De novo design and experimental characterization of ultrashort self-associating peptides. PLoS Comput. Biol. 10, e...
[59] found that one-third of the patients in ICU had an amikacinCmax< 60 mg/L with the recommended dose of 15 mg/kg of total body weight. This suggests the need for dose optimization based on creatinine clearance, total body weight and positive 24-h fluid balance in order to reach ...
In terms of vestibular function, while canal dysfunction and/or spontaneous nystagmus have been occasionally observed in this animal model,4,5 episodes of vertiginous attack or balance disorder have only rarely been observed.6 In other words, this model is insufficient for fully representing the ...
Kaki R, Elligsen M, Walker S, Simor A, Palmay L, Daneman N. Impact of antimicrobial stewardship in critical care: a systematic review. J Antimicrob Chemother. 2011;66:1223–30. Article CAS PubMed Google Scholar Montero JG, Lerma FÁ, Galleymore PR, Martínez MP, Rocha LÁ, Gaite...
The jet energy resolution is estimated both in data and in simulation using transverse momentum balance studies in dijet events, and they are found to be in good agreement [33]. Monte Carlo studies are used to assess the dijet mass resolution. Jets constructed from final state particles are ...