atopic dermatitisJanus kinase inhibitorsphosphodiesterase 4 inhibitorThis review aims to provide a summary of current knowledge on new topical and oral non-biological therapies recently approved for Atopic Dermatitis (AD) treatment.#The immense research carried out in the last decade has focused on ...
dandruff and thickened psoriasis-like symptoms in cynomolgus monkeys, indicating that it has strong biological activity in vivo. At the same time, through the modification of the Fc segment, the ADCC and CDC functions of HB0034 were weakened or even eliminated to a certain extent...
Alase A, Seltmann J, Werfel T, Wittmann M (2012) Interleukin-33 modulates the expression of human β-defensin 2 in human primary keratinocytes and may influence the susceptibility to bacterial superinfection in acute atopic dermatitis. Br J Dermatol 167(6):1386–1389 Article CAS PubMed Google ...
especially T cells and B cells are overactivated and recruited to cause self-tissue damage.1,2By far, researchers have discovered about 150 types of autoimmune diseases and adopted a series of treatment measures.3The diversity and rapid
The introduction of biological agents at the beginning of the twenty-first century has changed the way we treat several skin diseases, including chronic urticaria, psoriasis, atopic dermatitis, hereditary angioedema, hidradenitis suppurativa, pemphigus, lymphoma, lupus, and others diseases, providing more...
Berdyshev Pediatric Atopic Dermatitis Is Associated With More Rapid Recovery of Protein Bound Ceramides After Treatment With Dupilumab Poster #625Poster Session March 2, 20259:45 a.m. – 10:45 a.m. PST Goleva The Abnormal Metabolomic Activity in Atopic Dermatitis Skin Is Restored With Dupilumab...
There has been a paradigm shift in the treatment of various chronic dermatoses using biological drugs. We aim to describe the characteristics of patients w... HG Teo,SL Lai,IPL Ting,... - 《Malaysian Journal of Dermatology》 被引量: 0发表: 2024年 加载更多研究...
Molecular Psychiatry publishes work aimed at elucidating biological mechanisms underlying psychiatric disorders and their treatment A Petronis,II Gottesman,TJ Crow,... - 《Molecular Psychiatry》 被引量: 1104发表: 2000年 Stabilization and destabilization of soil organic matter—a new focus Interest in soi...
In summary, machines have great potential in drug discovery, especially when dealing with complex information. Through deep learning, machines can quickly find patterns and accelerate new drug discovery. Second, collaboration is key. A super-team of computer, biological and pharmaceutical experts is th...
next-in-class, i.e., novel chemical or biological entities that exploit a molecular mechanism already available for the treatment of the same condition (Table1). Table2breaks down the approvals according to the molecular structure (small molecule, antibody, peptide and protein, cellular and gene...