FIGS. 4band 4cshow the cell sample of FIG. 4awhen derived parameters are incorporated to create scattergrams. FIG. 4bshows the elongation of the neutrophil population402balong the P1 axis. FIG. 4cshows the spreading of the neutrophil population402crelative to the P2 axis, when that derived me...
Normal n = 7, ADHF n = 7, Baseline n = 7, CXCL-1 n = 6, CXCL-8 n = 5, CCL-3 n = 7. ***p≤ 0.001, ****p < 0.0001 relative to control by one-way ANOVA with Dunnett's post-test. Scale is 0.03 μm/s for control and 0.10 μm/s for ADHF. 4. Discussion We ...
For cells that maintain persistent polarity, such as neutrophils, there are several models describing how long-range communication underlying directional decisions might occur. A longstanding model in the field, abbreviated as LEGI (local-excitation-global-inhibition), suggests that, in addition to gener...