(mpo and elastase). nets, which were initially described by brinkmann in 2004, function as bactericidal traps that effectively promote the elimination of extracellular bacteria 12 . the mesh-like nets trap, neutralize, and eradicate a wide range of microorganisms, including bacteria (gram-positive ...
"In addition to her role as a The Health Board editor, Niki Foster is passionate about educating herself on a wide range of interesting and unusual topics to gather ideas for her own articles. A graduate of UCLA with a double major in Linguistics and Anthropology, Niki's diverse academic ba...
www.nature.com/scientificreports OPEN received: 28 January 2016 accepted: 20 May 2016 Published: 22 June 2016 Attenuated viral hepatitis in Trem1−/− mice is associated with reduced inflammatory activity of neutrophils Jan-Hendrik Kozik1, Tanja Trautmann1, Antonella Carambia1, Max ...
confirming the formulation’s safety for intravenous injection (Figure S2). Cytotoxicity studies revealed no significant inhibitory effects on the 4T1 tumor cells and DC cells within a specified concentration range (FigureS3), indicating the high biological safety of this ...
Thromboinflammation is a common complication observed in broad range of human disorders or pathological conditions, playing a significant role in their progression and clinical outcomes. This phenomenon occurs most commonly in deep vein thrombosis, stroke, atherosclerosis, systemic inflammatory responses (e...
A threshold tryptase value of more than 8.9 mu g/l seems to be sufficient for recommending further specialised examinations (specificity 85.6%, sensitivity 60%). All the children with a high tryptase level were referred for consultation with a specialist. Serum tryptase assay should be ...
ParametersAsthmatic children premedication (n = 48)Asthmatic children post medication (n = 48)p-Value PMA (CL-mV) Median 398.55 245.35 0.08 Range 1494 1363 Interquartile range 280.80 244.30 OPZ (CL-mV) Median 1517.45 1171 0.04 Range 3551.70 4002.60 Interquartile range 1144.37 1913.20 CL ...
range of priming and activating agonists has been well characterised, however the respiratory burst function of ovine neutrophils has been less well characterised. There have been fewer reports of ovine neutrophil respiratory function, and these studies are limited due to either: the methodology used,...
as has been reviewed extensively52. Nevertheless, our analysis indicates that a group of genes exists from which neutrophils preferentially draw when they become activated across humans and mice and across a large range of conditions and disease states. The conservation of a small set of transcriptio...
Neutrophils and macrophages were treated with saline (PBS, 0 nM TSP-1) or TSP-1 (1, 10 or 100 nM). Results are expressed as fold change over the PBS (0 nM TSP-1) control group. Boxes show median (centre line) and interquartile range (edges), whiskers show the range of va...