Monocytes represent key cellular elements that contribute to the neurological sequela following brain injury. The current study reveals that trauma induces the augmented release of a transcriptionally distinct CD115+/Ly6Chi monocyte population into the c
Activation state of neutrophils was determined by quantification of the percentage of CD86+ and CD206+ cells with gates set according to fluorescence minus one controls for each organ. Another cohort of mice was used to determine ROS production and to quantify the maturity level of neutrophils (...
In aseptic meningitis the mean absolute neutrophil count was 182, 164, 79, and 68 cells/mm3, respectively (P = 0.025). In bacterial meningitis the absolute neutrophil count was 28, 1,466, 5,853, and 235 cells/mm3, respectively. The mean percentage of polymorphonuclear cells in aseptic ...
Percentage of macrophages (A) or dendritic cells (B) stained with 7-Amino-Actinomycin-D (7AAD) after incubation with culture medium alone, with NETs or NETs supernatants. 7-AAD positive cells represent dead cells and were evaluated at 0.5, 3, 6, 12 and 24h post-stimulation. *P = 0.0...
Area under the receiver-operating curve (ROC) curves (AUC) of PCT, hsCRP and NLR (absolute neutrophil count to the absolute lymphocyte count) were 0.756, 0.617 and 0.612. The AUC of other biomarkers was ≤0.6. In addition, PCT, hsCRP, NLR and fibrinogen (Fg) were significantly ...
Low exposure to microbial products, respiratory viral infections and air pollution are major risk factors for allergic asthma, yet the mechanistic links between such conditions and host susceptibility to type 2 allergic disorders remain unclear. Through
(turning into debris) during the process, the most accurate measurement for neutrophil death is the absolute number of neutrophils at each time point, rather than the percentage. Although the percentages of healthy (PI/AV-negative) cells in theGsdmeKO group were lower compared with WT, there ...
High variability in the percentage of PR3-high (%PR3-high) neutrophils was observed in healthy volunteers and patients with inflammatory disease, and the %PR3-high was significantly greater in the patients (72 +/- 19% vs 55 +/- 20%, P < 0.0001). Overall neutrophil PR3 expression in ...
We aimed to investigate whether peripheral blood cell counts are associated with LPBC.METHODS:We evaluated the percentage of stromal TILs in breast cancer patients who underwent primary surgery, using the standardized methodology proposed by the international TIL Working Group. Lymphocyte-predominant breast...
Categorical data were presented as absolute value and percentage. Such data were compared using Chi-square test or Fisher’s exact test according to test assumptions. Correlation analysis was performed using Kendall's rank correlation tau. Statistical analysis was performed using R software11. Results...