Neutrophil extracellular traps as a potential marker of systemic lupus erythematosus activityBackground The heterogeneity of systemic lupus erythematosus (SLE) poses a significant challenge in identifying bioma
Neutrophils release their chromatin into the extracellular space upon activation. These web-like structures are called neutrophil extracellular traps (NETs) and have potent prothrombotic and proinflammatory properties. In ST-elevation myocardial infarction (STEMI), NETs correlate with increased infarct size....
Neutrophil extracellular traps (NETs) protect against infection, but they are also implicated in the pathology associated with various immune-mediated conditions. This Review describes when and how they are formed, how they function and how they are regu
中性粒细胞胞外杀菌网络,通常简称为NETs(Neutrophil Extracellular Traps),是中性粒细胞在面对病原体时释放的一种网状结构。这种结构由DNA、组蛋白和抗菌蛋白组成,可以捕捉和杀灭病原体,从而限制感染的扩散。注:《詹韦免疫生物学》9th中文版将Neutrophil Extracellular Traps翻译为“中性粒细胞胞外杀菌网络”,p639名词解...
NETRGs, neutrophil extracellular traps-related genes; HCC, hepatocellular carcinoma; TCGA, The Cancer Genome Atlas; CNV, copy number variation; GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes. The NETRGs were functionally annotated by GO and KEGG enrichment analyses. Leukocyte ...
Regulation of neutrophil activation is critical for disease control. Neutrophil extracellular traps (NETs), which are web-like structures composed of DNA and neutrophil-derived proteins, are formed following pro-inflammatory signals; however, if this pro
半滑舌鳎中性粒细胞胞外陷阱(neutrophilextracellulartraps,NETs)的产生特征与抗菌作用是当前生物学研究的重要课题。下面将进一步探讨这一主题。 一、半滑舌鳎中性粒细胞胞外陷阱的产生特征 半滑舌鳎的中性粒细胞胞外陷阱的产生是一个复杂的生物学过程。当机体遭遇病原微生物入侵时,中性粒细胞会迅速响应,通过一系列的生...
Chronic obstructive pulmonary disease (COPD) is characterised by persistent airway inflammation even after cigarette smoking cessation. Neutrophil extracellular traps (NETs) have been implicated in COPD severity and acute airway inflammation induced by s
tion of extracellular traps. During phagocytosis, internal- ized pathogens are translocated to phagosomes where the antimicrobial factors derived from granules and reac- tive oxygen species (ROS) create a killing environment for pathogens. The second mechanism, degranulation, is ...
forming the pathological basis of various diseases. In recent years, the critical role of neutrophil extracellular traps(NETs) in vascular barrier injury has gradually received attention. In this paper, the research progress on the involvement of NETs in vascular endothelial injury in autoimmune disease...