2011 American Chemical Society Middle School Chemistry Unit Chapter 6, Lesson 9: Neutralizing Acids and BasespH is a measure of the concentration of H 3O+ ions in a solution.Adding an acid increases the concent
When an acid and a base react with each other, a neutralization reaction occurs, forming a salt and water. The water forms from the combination of the H+ions from the acid and the OH-ions from the base.Strong acidsandstrong basescompletely dissociate, so the reaction yields a solution with...
Antibody engineering technologies face increasing demands for speed, reliability and scale. We develop CeVICA, a cell-free nanobody engineering platform that uses ribosome display for in vitro selection of nanobodies from a library of 1011 randomized seq
In this study, we designed and produced a prefusion GPC trimer antigen of LASV, named GPCv2. Based on the structural information of GPC, we made modifications by replacing the amino acid at position 328 with proline and appending the trimerization domain. This resulted in a highly expressed ...
The acids contained in the malodor neutralizing compositions invention described in this disclosure include citric acid undecylenic acid and monocarboxylic acids of the general formula R—COOH (VIII), in which in R is C1-C5 alkyl or is a C3 or C4 alkylene optionally substituted by phenyl...
Lassa virus (LASV) belongs to the Arenaviridae family and causes severe hemorrhagic fever in humans. Although many vaccine candidates for Lassa fever exist, no vaccines have been approved for clinical use currently. The precursor glycoprotein complex (GP
To remove the reads that contained adaptor contamination, low-quality bases, and undetermined bases, we performed read trimming using Cutadapt and Perl scripts [25]. Subsequently, sequence quality was verified using FastQC (http://www.bioinformatics.babraham.ac.uk/projects/fastqc/), including the ...
These isolated nucleic acids and the expression vectors comprising them may be used to express the antibodies of the invention or antigen binding fragments thereof in recombinant host cells. Thus, the invention also provides host cells comprising isolated nucleic acids comprising a sequence of ...
All PCR products were sequenced and any sequence with evidence of mixed bases was excluded from further analysis. For virus production amplicons were cloned into pcDNA3.1/V5-His-TOPO-TA (Invitrogen) and then sequence confirmed (to exclude cloning introduced changes). Envelope...
Because uncertainty in the UCA inference is highest for the bases in the CDR3 region, precise determination of some mutations in this region is not feasible and we therefore ignored the CDR3 region in our analysis of the representative set of bnAbs. In the simulations, we prohibited any ...