Yada, "Ghrelin directly interacts with neuropeptide-Y-containing neurons in the rat arcuate nucleus: Ca2+ signaling via protein kinase A and N-type channel-dependent mechanisms and cross-talk with leptin and orexin," Diabetes, vol. 52, no. 4, pp. 948-956, 2003....
Caloric restriction is an anti-aging intervention known to extend lifespan in several experimental models, at least in part, by stimulating autophagy. Caloric restriction increases neuropeptide Y (NPY) in the hypothalamus and plasma ghrelin, a peripheral gut hormone that acts in hypothalamus to modula...
Neuropeptide Y (NPY) is a sympathetic neurotransmitter widely distributed in the peripheral and central nervous system, affecting many physiological functions. Consequently, dysregulation of the NPY system contributes to numerous pathological disorders, including stress, obesity, and cancer. The pleiotropic ...
Because such adiposity was thought to be mediated by hypothalamic NPY neurons, we investigated by which mechanism a synthetic ghrelin receptor agonis... M Tschöp,MA Statnick,TM Suter,... - 《Endocrinology》 被引量: 324发表: 2002年 Neuropeptide Y (NPY) and sympathetic control of blood flow...
Previously we showed that neuropeptide Y and ghrelin induced discriminative stimulus effects similar to 2- hours food deprivation. In the present study we asked if opioid agonists would induce similar effects. After acquisition of the ... E O’Hare,J Cleary,DT Weldon,... 被引量: 0发表: 1998...
Objective Insulin, ghrelin, neuropeptide Y (NPY) and leptin interact in the regulation of energy homeostasis. Most of these signals are altered in polycyst... D Romualdi,LD Marinis,G Campagna,... - 《Clinical Endocrinology》 被引量: 37发表: 2008年 Lack of association between impaired glucose...
Related to neuropeptide:Neuropeptide Y neu·ro·pep·tide (no͝or′ō-pĕp′tīd, nyo͝or′-) n. Any of various short-chain peptides found in brain tissue, such as endorphins. American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin...
Neuropeptide Y (NPY) plays important roles in the central control of appetite and energy balance, but the receptor subtype responsible for this function has not been cloned. Here we report the cloning by expression of a novel NPY receptor subtype from a rat hypothalamus cDNA library. The novel...
CONTEXT: Anorexia nervosa (AN) presents an adaptive appetite regulating profile including high levels of ghrelin and 26RFa (orexigenic) and low levels of leptin and PYY (anorexigenic). However, this adaptive mechanism is not effective in promoting food intake. The NPY/proopiomelanocortin (POMC) sy...
While isoalliin is a core component of onion, the effects of isoalliin on feeding behavior and feeding centers remain unknown. Neuropeptide Y (NPY) and ghrelin are the most potent central and peripheral inducers of appetite. A Japanese kampo medicine Ninjin'yoeito activates ghrelin-responsive NPY...