In the inner retina, the number of rod and cone bipolar cells remained similar to controls, but abnormal GABAergic amacrine cell stratification and 25% reduction of rod bipolar cell axon terminals were observed. Brn3a staining revealed a 20% loss of retinal ganglion cells, which exhibited ...
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It is well known that the visual field (VF) defects are not uncommon in eyes with pathologic myopia. It has not been clear if such VF defects which are not explained by myopic chorioretinal lesions are due to glaucoma or some other causes especially in e
into two groups: (1) a group of patients with retinal neuronal loss, defined as thinning of the average GCC in at least one eye, compared to the normative data; and (2) a group of patients without retinal neuronal loss, if the OCT results were within normal limits in both eyes. All...
Levin, MD, PhD Archives of Ophthalmology Nonarteritic anterior ischemic optic neuropathy (NAION) is the most common cause of acute optic nerve disease in the elderly and often results in severe visual loss.1 The average annual incidence has been estimated at 2.3 to 10.2 per 100 000 persons ...
One week after the first visit, the VA levels decreased to 0.06 and 0.07 in the right and left eyes, respectively. Because the patient had a 7-month history of linezolid treatment for persistent pyogenic arthritis, we suspected linezolid-induced optic neuropathy and immediately terminated treatment...
Objective tests for detecting optic nerve disease are lacking. In particular, the researchers wanted to find a way to detect nerve disease in a single eye so that patients with bilateral involvement could be accurately diagnosed and monitored. ...
the anterior horn cells (“owl eyes”) may be seen on axial images; pencil-like enhancement of the anterior spinal cord on sagittal views is also suggestive (Zalewski et al., 2019) (Fig. 15.17). Importantly, MRI can be normal at presentation in nearly a quarter of cases; therefore, ...
The optic nerve is subject to a variety of mechanical forces in highly myopic eyes. Alterations in the circulatory supply of the nerve can be demonstrated in these eyes as well, making them susceptible to optic nerve damage. However, recognition of optic nerve abnormalities in highly myopic eyes...
is a peculiar disorder. It has a predilection for eyes with very small cup-disc ratios, causes predominantly inferior altitudinal visual field defects, and, like Thor's hammer, rarely strikes the same eye twice. Vision is lost rapidly, usually within days. However, in a small fraction of pat...