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et al. PPARbeta agonists trigger neuronal differentiation in the human neuroblastoma cell line SH-SY5Y. J Cell Physiol 211, 837-847, doi: 10.1002/jcp.20996 (2007).S. Di Loreto, B. D'Angelo, M.A. D'Amico, E. Benedetti, L. Cristiano, B. Cinque, M.G. Cifone, M.P. Ceru, C. ...
The characteristics, culture conditions and usefulness of the human neuroblastoma cell line SH-SY5Y as a model for axonopathy are presented in this chapter. It is described how the cell line can be differentiated to mature neurons by using serum-free "N2" medium supplemented with retinoic acid....
Another example is the humanneuroblastomacell line SH-SY5Y, which can synthesize dopaminein vitroand differentiatein vivo. Still, a puzzling observation seen, as discussed earlier, with primary cell grafts too is that in parkinsonian animal models the functional benefit postgrafting may not be due ...
method, the SH-SY5Y neuroblastoma cell line is differentiated to neuronal cell which expresses NSE, neuronal marker, and dopamine transporter (DAT) by treatment with all-trans-retinoic acid. SH-SY5Y cells allow investigating neuronal phenotypes of mental disorders as an in vitro model of these ...
To obtain some insight into the mechanisms of cell death involved in neurodegenerative diseases, we studied the effect of 1-methyl-4-phenylpyridinium (MPP+) on the human neuroblastoma cell line SH-SY5Y (a widely used model of Parkinson's disease). We found that MPP+ predominantly induced non-...
We report that MAST1 is upregulated during neuronal differentiation of the human neuroblastoma cell line, SH‐SY5Y. Inhibition of MAST1 expression by RNA interference attenuated neuronal differentiation of SH‐SY5Y cells. Cell cycle analyses revealed that MAST1‐depleted cells did not undergo cell ...
To obtain some insight into the mechanisms of cell death involved in neurodegenerative diseases, we studied the effect of 1-methyl-4-phenylpyridinium (MPP+) on the human neuroblastoma cell line SH-SY5Y (a widely used model of Parkinson's disease). We found that MPP+ predominantly induced non-...
Article CAS PubMed Google Scholar Liu Y, Fu Y, Zhang Y, Liu F, Rose GM, He X (2020) Butein attenuates the cytotoxic effects of LPS-stimulated microglia on the SH-SY5Y neuronal cell line. Eur J Pharmacol 868:172858 Article CAS PubMed Google Scholar Download references ...
We analysed the effect of ES on the neuronal morphology of the human neuroblastoma cell line SH-SY5Y and compared it to the effect of BDNF. SH-SY5Y has been treated with RA for 5 days to stop proliferation and initiate differentiation. Then, cells were exposed to ES with regimes described ...