When utilized in a supervised learning setting, the aim of the eSNN learning method is to produce and update a repository of output neurons, each of them labeled with a certain class label. In this classification context, the eSNN training algorithm is algorithmically described in Algorithm 1. ...
magenta). Arrowheads indicate double-labeled neurons (Chx10:GFP+ChAT+).bA sample stack from the central canal area showing the presence of V2a-IN (Chx10:GFP+) axonal collaterals (green) close to CB+NSPCs (magenta) with analysis of the proportion of the CB+NSPCs that are in ...
To monitor the responses in each cell type, we labeled neurons with R-GECO driven by the neuron-specific promoter synapsin and astrocytes with GCaMP6 driven by the astrocyte- specific promoter GFAP. We found that neurons can modify the calcium dynamics in astrocytes (Figures 4d–i). For ...
Individual tdTomato labeled SGNs could be traced from their cell bodies to the organ of Corti, shown in a top down (XY) view (top). Position in the OSL was assessed in cross-sectional (XZ) views through confocal image stacks (below). CALB2 intensities in cell bodies and processes were ...
(D) Venn diagram showing the intersection of downregulated genes in the I/R group (compared to Sham group) and upregulated genes in the Dex group (compared to I/R group); (E) Bar graph of GO and KEGG enrichment analysis of all intersecting genes; (F) Dendrogram of GO and KEGG ...
(N/A,Figure 4g). To monitor the responses in each cell type, we labeled neurons with R-GECO driven by the neuron-specific promoter synapsin and astrocytes with GCaMP6 driven by the astrocyte-specific promoter GFAP. We found that neurons can modify the calcium dynamics in astrocytes (Figures...
software (Pixmeo SARL, Bernex, Switzerland). The cortical thickness, hippocampal volume, and brain volume were manually labeled by an experimenter that was blinded to the genotype of mice. Measurements were obtained from a continuous series of slices (for cortical thickness: from +0.63 to −0....
Cell fate and proliferation ability can be transformed through reprogramming technology. Reprogramming glioblastoma cells into neuron-like cells holds great promise for glioblastoma treatment, as it induces their terminal differentiation. NeuroD4 (Neuron
Regulation of codon optimality is an increasingly appreciated layer of cell- and tissue-specific protein expression control. Here, we use codon-modified reporters to show that differentiation of Drosophila neural stem cells into neurons enables protein e
(Supplementary Fig.5). Intriguingly, we noticed that the number of GFP+ labeled cells inRnd2-deleted animals was consistently lower compared to control animals 2–3 weeks after retroviral injection (Fig.2A). In order to understand if Rnd2 expression is relevant to the survival of adult ...