The authors also detail strategies that are likely to be required to improve clinical studies moving forwards. Kiterie M. E. Faller Helena Chaytow Thomas H. Gillingwater Review Article02 Jan 2025 Acceptable performance of blood biomarker tests of amyloid pathology — recommendations from the ...
Number two:amyotrophic lateral sclerosis. There is a small subgroup, 1%-2% of patients, who have mutations in theSOD1gene. There is now a new antisense oligonucleotide calledtofersen, which reduces the concentration of SOD1 [protein] in the cerebrospinal fluid. There is a clinical phase 2 tria...
gait impairment, pseudobulbar affect, and cognitive deficits should be carefully considered in clinical assessments, monitoring, and multidisciplinary interventions. 肌萎缩性侧索硬化症 (ALS) 主要与运动皮层,皮质脊髓束 (CST),脑干和脊髓变性有关,而小脑受累的特征则少得多。然而,ALS的一些主要临床特征,如构音...
Addressing Healthcare Inequities: Bridging the Gap in Multiple Sclerosis – A Focus on Clinical and Healthcare Disparities in Black Patients View More Burst Expert Illustrations & Commentary™: Visualizing the Implications of Anti-Complement Therapies on Generalized Myasthenia Gravis ...
Author information: (1)ALS Clinical Research Center, University of Wisconsin Hospital and Clinics, Clinical Science Center, Madison 53792-5132. Benjamin Rix Brooks MD - 《Journal of the Neurological Sciences》 被引量: 3619发表: 1994年 JAMA Network | Archives of Neurology | Frontal-Subcortical Circu...
Structural differences in 40- and 42-residue-long amyloid-β fibrils seeded in vitro from the cortical tissue of patients with different clinical subtypes of Alzheimer’s disease suggest that different fibril structures form in different disease variants and with different peptide lengths. Wei Qiang ,...
Neurology refers to the field of medicine that focuses on the diagnosis and treatment of various neurological disorders, including epilepsy, stroke, dementia, and movement disorders. From:Clinical Neurotoxicology,2009 About this page Add to MendeleySet alert ...
The repurposing of drugs with established safety profiles from their use in other human diseases is a new approach to therapeutic discovery in ALS. Enhanced clinical trial designs, including multi-arm, multi-stage platform trials, that incorporate biomarkers of treatment responses will accelerate drug ...
Educational Objective: To recognize the clinical importance of misdiagnosis of ALS. St Louis Encephalitis: A Review of 11 Cases in a 1995 Dallas, Tex, EpidemicArticle Educational Objective: To update knowledge about clinical features of Saint Louis encephalitis. Multifocal Dural Enhancement Associated Wi...
The neuromuscular condition center is a resource for clinical news on the diagnosis, treatment, and management of neuromuscular conditions. | NeurologyLive.