Neurological manifestations of acute COVID-19 include headache, peripheral neuropathies, seizures, encephalitis, Guillain鈥揃arr茅 syndrome, and cerebrovascular disease. Commonly reported long term neurological sequelae of COVID-19 are cognitive dysfunction and dysautonomia, which despite being associated ...
This patient was clinically diagnosed with ZIKV infection, and 1 month later went to the medical center with areflexia, paresthesia, upper and lower symmetric muscle weakness, tingling or prickling sensations in fingers and toes, dysautonomia, and difficulty in walking steadily. This made a ...
28 Signs and symptoms include spastic paraparesis, extensor plantar response, and impaired position and vibratory sense.2, 29 Subacute combined degeneration of the spinal cord occurs in 15% of patients with megaloblastic anemia. Dysautonomia and peripheral neuropathy is found in 40%, and optic ...
The current evidence for direct viral invasion of neurons occurring in human patients is conflicting, with certain groups describing frequent viral presence [22,23,24,25], but many others finding no evidence of it at all [23,26,27,28,29], suggesting a substantial impact of technical approach....
Uncertainty remains with respect to the capacity of these means to decrease the risk of cardiovascular mortality in patients who have chronic cardiac dysautonomia due to mental illness. In the following, our studies on the role of neurocardiac autonomic function in psychopharmacology as well as the...
The present review focuses on the recent advancements in modeling neurological disorders, including the demonstration of disease-specific phenotypes in iPS cell-derived neurons generated from patients with spinal muscular atrophy, familial dysautonomia, Rett syndrome, schizophrenia and Parkinson disease. The...
Objective: To report a case of atypical neurological manifestations associated with ganglionic nicotinic acetylcholine receptor (伪3-AChR) autoantibody.Background: The ganglionic nicotinic acetylcholine receptor autoantibody (伪3-AChR Ab) typically causes subacute or insidious onset autoimmune dysautonomia. ...
Multiple seizure types were described, often in the same individual, with absence seizures as the most common in 29% (29/100) of the cohort overall and in 69% (29/42) of those with seizures. We saw a number of symptoms that may be features of dysautonomia. Just under half of ...
While this study did not show whether these compounds can elevate SMN levels or rescue the loss of patient-derived motor neurons, it provided an important validation for the utility of iPS-derived patient cells to model disease. Familial dysautonomia Familial dysautonomia (FD) is one of the ...
335 (12%) of the symptomatic patients were diagnosed with dysautonomia, and the diagnosis was mainly performed by a neurologist (55%), a rheumatologist (21%) or a cardiologist (13%). Treatment was prescribed to 596 (99%) of patients diagnosed with SD-neurological manifestations, but only ...