The first example of using patient-derived iPS cells to model any human disease was for the study of spinal muscular atrophy (SMA) (Ebert et al., 2009). SMA is an autosomal-recessive disease characterized by the selective degeneration of lower motor neurons in the brainstem and spinal cord,...
Class A includes BCI applications that record signals from the brain to interface with an external system due to motor impairment from neurologic disease or injury (e.g., spinal cord injury, amyotrophic lateral sclerosis (ALS), brainstem stroke). These external systems include but are not limited...
Positional vertigo and positional nystagmus (paroxysmal, persistent or both) can be the presenting feature of some focal lesions and diffuse diseases affecting the cerebellum or the brainstem [58,59,60]. Downbeating nystagmus on straight head-hanging, upbeating nystagmus on returning to the upright ...
A Case of Fulminant Listeria Rhombencephalitis with Brainstem Abscesses in a 37-Year-Old Immunocompetent Patient: From Vestibular Neuritis to Ondine's Curse Cheng, Sitong; Zhang, Yue; Ou, Cehua; Li, Fubo: Postherpetic Trigeminal Neuralgia of the V2 Branch Treated with Electrodes Placed through th...
(longitudinally transverse myelitis extending across three or more vertebral segments) may be accompanied by brainstem or brain symptoms (area postrema syndrome, diencephalic syndrome, or other brainstem disorders). Cases are more frequent in people not of European descent. Most patients meeting the ...
Conclusion Seminoma can cause PNS showing 8th cranial nerve palsy, cerebellar, and brainstem atrophy with hot cross-bun sign on MRI study. Extensive screening for onconeural antibodies was negative and thereby suggested that unknown antibodies worked for both antitumor immunity and induction of PNS....
Although dysphagia has been reported as a symptom of CNS disease for almost two centuries,7, 8 it was generally believed that bilateral hemispheric or brainstem damage must occur to produce dysphagia. Clinical evaluation and postmortem brain studies9 and cortical stimulation studies in humans,10 howev...
peripheral nervous system (PNS) autoimmune disease, usually established following infection. GBS, Fisher syndrome (FS), and Bickerstaff brainstem encephalitis (BBE) are considered as GBS-related disease (GBSRD). Anti-glycolipid antibodies are raised in GBSRD and involved in the pathogenesis. The ...
A cough may be the initial symptom in patients with Chiari I malformations due to lesions in the dorsal medullary region of the brainstem. A space-occupying brainstem lesion involving the cough center or compressing on the efferent fibers can be a rare cause of chronic cough[16]. NMOSD NMOSD...
Significant elevation of CSF IL-6 levels and motor dominant neuropathy in a severe case of Surfer's myelopathy due to an exercise unrelated to surfing Hiroto Mitsuyoshi, Atsushi Kadowaki, Tatsuhiko Ozono, Yasuyoshi Kimura, Hideki Mochizuki Article 123448 select article Cerebello-brainstem dominant form...