In addition to their expression by sensory nerves, TRPV1, TRPA1, PAR-2, and PAR-4 are found in resident skin cells or cells recruited during CNI. Thus, they could contribute to the intense and narrow communication within the skin between sensory nerve endings, skin, and immune cells. This...
In a recently injured tetraplegic in spinal shock, tactile or painful stimuli originating below the level of the lesion induce no change in blood pressure or heart rate. In the chronic stages of spinal cord injury at the level of T6 and above, however, there is an exaggerated rise in...
After acute and severe SCI, a postinjury period, called spinal shock (SS), could start, which is characterized by several modifications mediated by spinal cord neuroplasticity [79,80,81,82]. SS represents a lack of descending facilitation after UMN lesions clinically determining LMN signs, and ...