神经纤维瘤病II型(Neurofibromatosis typeII, NF2),是一种少见常染色体显性遗传病,特征性表现为双侧听神经鞘瘤,主要表现为脑膜瘤和/或神经鞘瘤,单发或多发。神经鞘瘤可发生在第3一12对颅神经,最常发生于听神经,其次是三叉神经。较少出现皮肤症状和眼部表现,50%的病例有家族聚集性,目前,国际上公认的诊断标准:1、...
Neurofibromatosis Type 2Auditory-Vestibular NerveChromosome 22MeningiomasSchwannomasNeurofibromatosis type 2 (NF2) is an inherited disease which is mainly characterized by the development of multiple schwannomas and meningiomas. Incidence of the disease is about 1 in 60,000. Affected individuals inevitably ...
神经纤维瘤病II型(Neurofibromatosis typeII, NF2),是一种少见常染色体显性遗传病,特征性表现为双侧听神经鞘瘤,主要表现为脑膜瘤和/或神经鞘瘤,单发或多发。神经鞘瘤可发生在第3一12对颅神经,最常发生于听神经,其次是三叉神经。较少出现皮肤症状和...
2型神经纤维瘤病(neurofibromatosis type 2,NF2) 此病少见,但严重的常染色体遗传性疾病,在人群患病率为1/25 000,50%的患儿是从父母中遗传了此病。患者从出生开始这一生,都会在全身神经系统不断产生肿瘤,95%以上的患儿会在两侧的听神经上产生肿瘤,同时也可伴有或不伴有其他肿瘤、眼部病变和皮肤病变等。患者都会出...
Neurofibromatosis type 2 (NF2) A hereditary condition associated with an increased risk of bilateral acoustic neuromas, other nerve cell tumors and cataracts. Mentioned in: Acoustic Neuroma Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.Want...
neurofibromatosis type 2COREWSASdistresspsychosocial functioningquality of lifeOxford & SW NF2 Service, Neurosciences, The West Wing, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK Specialist Surgery Psychology Team, The Oxford Psychological Medicine Centre, Russell ...
Neurofibromatosis type 2 (NF2)Simon K.W. LloydD. Gareth R. EvansHandbook of Clinical Neurology
Neurofibromatosis type 2 (NF2) is a genetic condition marked by the development of multiple benign tumors in the nervous system. The most common tumors associated with NF2 are bilateral vestibular schwannoma, meningioma, and ependymoma. The clinical manifestations of NF2 depend on the site of involve...
Evans DG. Neurofibromatosis 2 [Bilateral acoustic neurofibromatosis, central neurofibromatosis, NF2, neurofibromatosis type II]. Genet Med 2009;11:599Y610Evans DG. Neurofibromatosis 2 Bilateral acoustic neurofi- bromatosis, central neurofibromatosis, NF2, neurofibroma- tosis type II. Genet Med 2009;11:...
Type 1 (NF1) causes skin changes and deformed bones. It usually starts in childhood. Sometimes the symptoms are present at birth. Type 2 (NF2) causes hearing loss, ringing in the ears, and poor balance. Symptoms often start in the teen years. ...