在基线时间、每3个月的治疗期间和结束治疗时进行生活质量(QoL)评估。 结果:2018年5月至2020年3月期间,共有7名患者接受了总共48次CED输注,中位年龄为8岁,范围为5-21岁。其中3名患者经历了剂量限制性毒性。观察到4例3级治疗相关不良事件。大...
Conclusion Longitudinal analyses generally indicate that the Neuro-QoL Cognitive Function measure is sensitive to change over time in individuals with HD. Neuro-QoL Cognitive Function changes reflect self-reported cognitive change at 12 and 24 months and performance-based change at 12 months. This ...
We conducted this study in two which involved a comprehensive literature search, patient and professional input, development of an initial item pool, cognitive interviews, and field testing across major neurological disorders (n=511). Item response theory analyses yielded an 18-item unidimensional bank...
Finally, for patients with glioma the quality of life (QoL) is an increasingly important recognized factor. Not only do these patients suffer from general symptoms associated with cancer, such as fatigue, anxiety, and depression, but also from seizures, cognitive deficits, and focal neurological ...
Random coefficient models were used to estimate the longitudinal trends in cognitive assessment scores.Results. Median neurocognitive follow-up was 9.8 years. There was a significant decline in short-delay recall (slope = -0.01 standard deviation [SD]/year, P < 0.001), total recall (slope = -...
Results: The lower extremity functioning score of the Neuro-QOL showed the highest correlations with MSFC-4 components including Timed 25-Foot Walk, 9-Hole Peg Test, and cognitive score. The expected domains of the Neuro-QOL showed high correlations with the SF-36 subscores, and some Neuro-...
We conducted this study in two which involved a comprehensive literature search, patient and professional input, development of an initial item pool, cognitive interviews, and field testing across major neurological disorders (n=511). Item response theory analyses yielded an 18-item unidimensional bank...
QOLP-12. EVALUATION OF THE UCLA NEURO-ONCOLOGY PROGRAM PSYCHOSOCIAL PATIENT SCREENING FORM IN IDENTIFYING DEPRESSION, FATIGUE, AND PERCEIVED COGNITIVE FUNCTION IN PATIENTS WITH GLIOMASGiven the high prevalence of neurobehavioral symptoms such as depression, fatigue, and cognitive dysfunction in patients ...
Longitudinal analyses generally indicate that the Neuro-QoL Cognitive Function measure is sensitive to change over time in individuals with HD. Neuro-QoL Cognitive Function changes reflect self-reported cognitive change at 12 and 24 months and performance-based change at 12 months. This measure may ...
Neuro-QoLPatient-centered outcomesPurpose Cognitive functioning impacts health-related quality of life (HRQOL) for individuals with Huntington disease (HD). The Neuro-QoL includes two patient-reported outcome (PRO) measures of cognition鈥擡xecutive Function (EF) and General Concerns (GC). These ...