Prospero E, Barbadoro P, Filippetti F, Appignanesi R, Ciavattini A, Carle F. Occurrence of neural tube defects in pregnancy: an excess of cases in a 2773-km2 area in Central Italy. J Toxicol Environ Health A. 2008;71(15):981-3....
The meaning of NEURAL TUBE is the hollow longitudinal dorsal tube formed by infolding and subsequent fusion of the opposite ectodermal folds in the vertebrate embryo that gives rise to the brain and spinal cord.
Maternal diabetes during pregnancy has well-documented teratogenic effects that cause birth defects such as cardiovascular malformations and neural tube defects. Those effects are not well understood, but are thought to involve interactions of the embryo's genetic makeup with the intrauterine environment....
Surgery may be done during pregnancy or after birth. After surgery, long-term care will be needed to treat conditions or disabilities caused by spina bifida.Help prevent neural tube defects:Talk to your healthcare provider if you are of childbearing age and plan to have a child. Your ...
We present data from a case series in France of pregnant women who lost 2 to 14 kg during the first month after conception and whose fetuses developed neural tube defects (NTDs). Preliminary epidemiologic evidence from other data sets suggest that relative lack of weight gain during pregnancy ma...
Periconceptional folic acid can reduce the occurrence of neural tube defects (NTDs) by up to 70%, and autoantibodies for folate receptors (FRs) have been observed in serum from women with a pregnancy complicated by an NTD. This population-based cohort study has examined serum from pregnant mot...
studies have found that a folic acid intake of 5 mg daily before conception and during the first month of pregnancy reduces the incidence of neural tube defects by 85%. Based on this evidence, the US Food and Drug Administration has ordered manufacturers to add folic acid to pasta, breakfast...
Neural Tube Defects and Spina Bifida - Learn about the causes, symptoms, diagnosis & treatment from the MSD Manuals - Medical Consumer Version.
Neural tube defect genes and maternal diabetes during pregnancy. Birth Defects Res A. 2010;88(8):601–11. https://doi. org/10.1002/bdra.20680. 6. Ornoy A. Valproic acid in pregnancy: how much are we endangering the embryo and fetus? Reprod Toxicol. 2009;28(1):1–10. https...
792 cases of pregnant women with adverse pregnancy outcomes and 4 492 cases of pregnant women with normal pregnancy outcomes.And 96 cases of foetuses with neural tube defects were screened as neural tube defects group while 120 normal pregnant women during the same period in our hospital were ...