A wide variety of social experiences, including sexual, parental, and housing experiences can facilitate "persistent" aggressive states, suggesting that these experiences engage a common set of synaptic and molecular mechanisms that act on dedicated neural circuits for aggression. It has long been ...
Females increase aggression for mating opportunities and for acquiring reproductive resources. Although the close relationship between female aggression and mating status is widely appreciated, whether and how female aggression is regulated by mating-related cues remains poorly understood. Here we report an ...
aggression, feeding, and sleep, but also select a single behavior for execution at any given time, depending on both internal states and external environmental conditions. Despite their tremendous biological importance, the neural mechanisms of action selection remain poorly understood. In the past deca...
Social context can dampen or amplify the perception of touch, and touch in turn conveys nuanced social information. However, the neural mechanism behind social regulation of mechanosensation is largely elusive. Here we report that fruit flies exhibit a s
Thus, other neuronal populations and molecular mechanisms may exist in BNSTEsr2 neurons to encode sexual satiety in females, which awaits further analysis. The work by Zhou et al. (2023) significantly advances our understanding of the neural encoding of the sexual satiety state. More importantly,...
K. et al. Innate and plastic mechanisms for maternal behaviour in auditory cortex. Nature 587, 426–431 (2020). Article ADS CAS PubMed PubMed Central Google Scholar Factor, E. M., Mayer, A. D. & Rosenblatt, J. S. Peripeduncular nucleus lesions in the rat: I. Effects on maternal...
To identify the biological mechanisms underlying different pathologies and to evaluate the efficacy of novel therapies, thousands of animal models of human disorders have been developed. For an animal model of a human disorder to be considered valid, it has to satisfy three criteria:construct,face,...
of reliable animal models due to the absence of consensus on the pathology and etiology of depression. Furthermore, the neural circuit mechanism of depression induced by various factors is particularly complex. Considering the variability in depressive behavior patterns and neurobiological mechanisms among...
Early life adversity (ELA) is a major risk factor for mental illness, but the neurobiological mechanisms by which ELA increases the risk for future psychopathology are still poorly understood. Brain development is particularly malleable during prenatal a
of the precise mechanisms underlying adaptation. For instance, if the volume of a region follows an inverted u-shaped trajectory that reaches its peak in youth, then a larger volume in childhood associated with adversity would suggest accelerated maturation. In contrast, the same pattern observed ...