Gysi, Deisy Morselli, et al. "Network medicine framework for identifying drug-repurposing opportunities for COVID-19." Proceedings of the National Academy of Sciences 118.19 (2021).https://doi.org/10.1073/pnas.2025581118 作者部署了依赖于人工智能、网络扩散(network diffusion)和网络接近性(network prox...
Network-medicine framework for studying disease trajectories in US veteransA better understanding of the sequential and temporal aspects in which diseases occur in patient's lives is essential for developing improved intervention strategies that reduce burden and increase the quality of health services. ...
Fig. 3: Network medicine framework. a WDD searches for gene–PND and drug–PND associations. All WDD results were filtered to keep only relationships supported by two documents or more and at least 50% confidence. b Selection of exclusive genes of each PND that are coexpressed in brain tissu...
One of the world's leading journals in the field of translational research, Journal of Translational Medicine is dedicated to turning fundamental discoveries ...
CGMega: explainable graph neural network framework with attention mechanisms for cancer gene module dissection Hao Li Zebei Han Xiaochen Bo Nature Communications(2024) Lacking mechanistic disease definitions and corresponding association data hamper progress in network medicine and beyond ...
Systems pharmacology and drug repurposing Multi-omics / multilayer networks in medicine Precision network medicine for personalized diagnostics and therapy Network-based approaches for undiagnosed or rare diseases Mobility, social network and electronic health record analysis for human well-being ...
Traditional Chinese medicine-based network pharmacology could lead to new multicompound drug discovery Evid. Based. Complement. Alternat. Med., 2012 (2012) Google Scholar Li, 2007 S. Li Framework and practice of network-based studies for Chinese herbal formula J. Chinese Integr. Med., 5 (2007...
If generic drug makers do not get aid in the face of soaring energy costs and potential shortages this winter, there could be production stoppages, the European Union of Generic Medicine Manufacturers warned in a statement open letter to the European Commission... Read... ...
Transcriptomics, metabolomics, proteomics and other -omics technologies have the potential to provide insights into complex disease pathogenesis and heterogeneity, especially if they are applied within a network biology framework. “Network medicine” is the rapidly developing field which applies systems ...
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