We also assessed the effect of shear stress on neutrophil responses to three other NET-inducing agents, PMA, LPS and ATP. Among these stimuli, ATP is generated abundantly in the cytosol through respiration and glycolysis pathways49. Extracellularly, ATP acts as autocrine and paracrine signalling mo...
The presence of the ATP-ADP system in both the networks could be explained considering that ATP is the main energetic source of spermatozoa. In fact in this cell, the metabolic energy production is fuelled by the glycolysis exclusively, by mitochondrial oxidative phosphorylation exclusively, or by ...
Bordetella pertussis bacteria can produce a toxin termed adenylate cyclase toxin (ACT), which can bind to host cells and translocate its catalytic domain into them, being able to produce cAMP from ATP. Catalytically active ACTs prevented PMA, cytosolic ROS-dependent NETs formation [33]. ...
Fill in the blank. In eukaryotic cells, respiration, other than glycolysis, take place in the ___. In cellular respiration, most of the ATP produced from glucose occurs during this step? A. Glycolysis B. Electron Transport Chain C. Tricarboxylic acid Cycle D. Electron tr...
The effect of inhibition of the mitochondrial ATPase with oligomycin on the rate of ATP depletion and anaerobic glycolysis was studied in the totally ischemic dog heart. An oxygenated, buffered crystalloidal solution containing 10 渭m oligomycin and 12 mm glucose was delivered at 100 mmHg pressure ...
(A)fructose-2,6-bisphosphate,(B)ATP,(C)ADP,(D)AMP,(E)CO2. Ifradioactiveinorganicphosphate(32~i) isaddedtoacellextractundergoingglycolysis,the32~icould bedirectlyincorporatedintoaglycolyticintermediatebywhichstep?(A) glucose+glucose-6-phosphate,(B)fructose-6-phosphate+fructose-1,6-bisphosphate,(C...
ATP-binding cassette transporter G2 MYC: Transcription factor c-Myc References Alaimo S, Rapicavoli RV, Marceca GP, La Ferlita A, Serebrennikova OB, Tsichlis PN, Mishra B, Pulvirenti A, Ferro A (2020) Phensim: phenotype simulator. bioRxiv.https://doi.org/10.1101/2020.01.20.912279 ...
(no HCO3−) andCboth Cl−and HCO3−. Arrows denote the addition of SLO, ATP, or CMA to the bath medium. The obtained ratios were transformed to pH values (mean ± SD, n ≥ 3/total number of cells used in the experiments) using an equation obtained from the calibration...
ATP, glycolytic intermediates and catabolites of the adenine nucleotide pool were measured in the control and treated beds at various intervals during 120 min of ischemia. Inhibition of the ATPase resulted in slowing of the rates of ATP depletion and anaerobic glycolysis (estimated by lactate ...
The voltage across the mitochondrial membrane drives ATP synthesis. High glucose levels enhance glycolysis, increasing electron donation to the ETC. This elevation in electron flux raises the membrane potential, leading to increased electron donation to oxygen, generating reactive oxygen species (ROS), ...