This chapter presents the structure and mechanism of action of nerve growth factor (NGF). NGF has been purified to homogeneity from the submaxillary gland of the adult male mouse and from the venom of the cobra Naja naja . Both proteins are dimers of identical polypeptide chains which have a...
prostate neuroendocrine-like cells play a role in promoting NEPC progression of non-neuroendocrine cells via activation of a muscarinic receptor has not yet been studied. We sought to study the communication mechanism between the NGF and CHRM4 to provide an exploitable target for effective NEPC treat...
(RA) causes bone destruction due to significantly more severe inflammation47,48,49. Thus, the repair mechanism in joints affected by RA is more devastatingly impaired. In contrast, osteoarthritic joints usually have active bony remodeling, which is thought to be a necessary pathophysiologic response ...
Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation. We have developed an experimental paradigm to study the mechanism by which nerve growth factor (NGF) allows the survival of sympathetic neurons. Dissociate... Martin,D. P. - 《Journal...
A., 1974, Nerve growth factor and insulin: Evidence of similarities in structure, function and mechanism of action, Rec. Prog. Horm. Res. 30 : 575.Bradshaw, RA, Hogue-Angeletti, RA, Frazier, WA (1974) Nerve growth factor and insulin: Evidence of similarities in structure, function and ...
美 英 un.神经生长因子 英汉 un. 1. 神经生长因子 例句 释义: 全部,神经生长因子 更多例句筛选
Neuronal SUMOylation: mechanisms, physiology, and roles in neuronal dysfunction.###The heat shock factor A4A confers salt tolerance and is regulated by ox... Contact inhibition is a crucial mechanism regulating proliferation in vitro and in vivo. Despite its generally accepted importance for maintain...
Our results suggest that NGF can up-regulate LNGFR expression at the mRNA and protein levels in cultured P3 basal forebrain cholinergic neurons and that this mechanism may play an important role in potentiating the effect of NGF on these neurons. 展开 ...
Mechanism of adrenomedullin-induced relaxation in isolated canine retinal arteries. PURPOSE: To analyze the mechanism of action of adrenomedullin (AM), a peptide recently isolated from human pheochromocytoma, in isolated canine central ret... T Okamura,K Ayajiki,K Kangawa,... - 《Invest Ophthalmol...
In order to assess a potential mechanism for such interactions, I have investigated the effects of the target-derived trophic molecule for sympathetic ganglion cells on the development of dendrites in the rat superior cervical ganglion. Systemic treatment of neonatal animals with NGF for 1 or 2 ...